Fecal Calprotectin in Patients Infected with Intestinal Protozoan Infections

NCT ID: NCT06890455

Last Updated: 2025-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-03-31

Study Completion Date

2026-02-28

Brief Summary

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Calprotectin extracted from stool can be detected easily using ELISA. Numerous studies have shown that fecal calprotectin concentrations demonstrate a good correlation with intestinal inflammation This study aims to detect the relationship between fecal calprotectin and Blastocystis hominis and Entamoeba histolytica infections.

Detailed Description

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Conditions

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Fecal Calprotectin in Intestinal Protozoa

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Study Groups

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Case group

40 patients complaining of gastrointestinal manifestations and infected with Blastocystis or Entamoeba histolytica

No interventions assigned to this group

Control group 1

40 persons complaining of gastrointestinal manifestations without any protozoal infections

No interventions assigned to this group

Control group 2

\- 40 healthy control cross-matched volunteers (without gastrointestinal manifestations, or intestinal parasites).

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

120 fecal samples will be collected as the following:

* 40 samples from patients complaining of gastrointestinal manifestations and only infected with B.hominis and E.histolytica.
* 40 samples from patients complaining of gastrointestinal manifestations without any protozoal infection.
* 40 healthy control cross-matched volunteers (without gastrointestinal manifestations, or intestinal parasites).

Exclusion Criteria

* persons received antiparasitic drugs or antibiotic 2 weeks before sample collection Patients with mixed intestinal protozoa Patients with intestinal protozoa rather than Entamoeba histolytica and Blastocystis
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Youstina Kamel Boles

Demonstrator of Medical parasitology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sohag University

Sohag, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Youstina Kamel Boles, Demonstrator

Role: CONTACT

+20 12 73435308

Facility Contacts

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Youstina Kamel Boles, Demonstrator

Role: primary

+20 12 73435308

Other Identifiers

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Soh-Med--25-3-07MS

Identifier Type: -

Identifier Source: org_study_id

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