Study of the Interactions Between Dientamoba Fragilis and the Gut Microbiota

NCT ID: NCT02534272

Last Updated: 2025-03-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

27 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-02-16

Study Completion Date

2019-03-29

Brief Summary

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D.fragilis is an intestinal protozoon that feeds by phagocytosis of intestinal bacteria. The study aim to determine if the carriage of the intestinal parasite D.fragilis is associated to changes of gut microbiota in subjects presenting with or without intestinal symptoms.

Detailed Description

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Conditions

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Diarrhea

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Symptomatic subjects

Subjects with intestinal symptoms

Stool sampling and sequencing of gut microbiota.

Intervention Type OTHER

Asymptomatic subjects

Subjects without intestinal symptoms

Stool sampling and sequencing of gut microbiota.

Intervention Type OTHER

Interventions

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Stool sampling and sequencing of gut microbiota.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* male/female aged at least of 18 years
* subject with abdominal pain, diarrhea, bloating
* no other known intestinal disease


* male/female aged at least of 18 years
* no known intestinal disease

Exclusion Criteria

* chronic intestinal diseases such as IBD, IBS …
* intake of antibiotic or probiotic within the 2 last months
* subject in exclusion period
* subject unable to understand information for a free consent to the study
* subject in safeguarding justice or guardianship
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Strasbourg, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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CANDOLFI Ermanno, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpitaux Universitaires de Strasbourg

Locations

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Laboratoire de Parasitologie et de Mycologie Médicale du Plateau Technique de Microbiologie des Hôpitaux Universitaires de Strasbourg

Strasbourg, , France

Site Status

Médecine interne, maladies tropicales et infectieuses Hôpital Civil

Strasbourg, , France

Site Status

Service de Médecine Interne - Diabète et Maladies métaboliques Hôpital Civil

Strasbourg, , France

Site Status

Service d'hépato gastro-entérologie et assistance nutritive Hôpital Hautepierre

Strasbourg, , France

Site Status

Countries

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France

Other Identifiers

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6110

Identifier Type: -

Identifier Source: org_study_id

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