Biomarkers and Unstable Carotid Plaque

NCT ID: NCT06887894

Last Updated: 2025-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-01

Study Completion Date

2027-12-31

Brief Summary

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This prospective study investigated associations between circulating miRNAs and symptomatic and asymptomatic ICAS, carotid plaque morphology and future cardiovascular events.

Detailed Description

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Conditions

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Carotid Artery Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Carotid endarterectomy

Carotid endarterectomy, plaque histological analysis and miRNA expression

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Presence of significant internal carotid artery stenosis referred to carotid artery endarterectomy.
* Age\>18 years

Exclusion Criteria

* Presence of significant internal carotid artery stenosis referred to carotid artery stenting
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

Sponsor Role lead

Responsible Party

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TINELLI GIOVANNI

Associate Professor of Vascular Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Fondazione Policlinico Universitario A. Gemelli IRCCS

Roma, RM, Italy

Site Status RECRUITING

Countries

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Italy

Facility Contacts

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Giovanni Tinelli

Role: primary

0039 0630157205

Other Identifiers

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0032543/19

Identifier Type: -

Identifier Source: org_study_id

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