Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars
NCT ID: NCT06880952
Last Updated: 2025-03-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
145 participants
INTERVENTIONAL
2021-09-01
2022-08-19
Brief Summary
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In this prospective, randomized controlled trial,130 patients who underwent mandibular third molar surgical removal were divided into two groups: one group used chlorhexidine for postoperative rinsing and the other did not rinse. Pain levels, measured using the Numeric Rating Scale (NRS), were recorded daily for the first seven days post-surgery. Paired-samples t-tests were utilized for data analysis.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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Post-operative rinsing with chlorhexidine
In the rinsing group, the patients received a bottle of 0,2% chlorhexidine
Chlorhexidine Digluconate Mouthwash without Alcohol
In the rinsing group, the patients received a bottle of 0,2% chlorhexidine
No post-operative rinsing
Those allocated to the control group received no post-operative rinsing
No interventions assigned to this group
Interventions
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Chlorhexidine Digluconate Mouthwash without Alcohol
In the rinsing group, the patients received a bottle of 0,2% chlorhexidine
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* planned coronectomy
* trismus
* chronic pain
* pregnancy
* known allergies to local anesthesia
18 Years
ALL
Yes
Sponsors
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Isala
OTHER
Responsible Party
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Jeroen van der Sleen
Oral Surgeon and Principal Investigator
Locations
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Isala Hospital
Zwolle, Overijssel, Netherlands
Countries
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References
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Ghaeminia H, Hoppenreijs TJ, Xi T, Fennis JP, Maal TJ, Berge SJ, Meijer GJ. Postoperative socket irrigation with drinking tap water reduces the risk of inflammatory complications following surgical removal of third molars: a multicenter randomized trial. Clin Oral Investig. 2017 Jan;21(1):71-83. doi: 10.1007/s00784-016-1751-1. Epub 2016 Feb 27.
Other Identifiers
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71727.075.20
Identifier Type: -
Identifier Source: org_study_id
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