Validation of the French Version of the Primary Lateral Sclerosis Functioning Rating Scale (PLSFRS)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-04-11

Study Completion Date

2026-06-30

Brief Summary

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This is a national, multicentric, prospective, descriptive study evaluating the psychometric properties of the French version PLSFRS scale

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Detailed Description

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This is a prospective study conducted in 8 French ALS centers which will enroll 80 patients with PLS. All these patients will undergo an evaluation of their functional status from the ALSFRS-r and PLSFRS scales. All patients will be evaluated at 3 time points (T0,M6 at the outpatient clinic) and at M3 remotely. The aim of the study will be to validate a trans-cultural and psychometric version of the PLSFRS available for the French PLS population.

Conditions

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Lateral Sclerosis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with a primary lateral sclerosis

Assessment of the functional status

Intervention Type OTHER

assessment of their functional status using the French version of the PLSFRS scale during a routine multidisciplinary assessment every 3-6 months for all patients with motor neurone disease, as recommended by the FILSLAN network

Interventions

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Assessment of the functional status

assessment of their functional status using the French version of the PLSFRS scale during a routine multidisciplinary assessment every 3-6 months for all patients with motor neurone disease, as recommended by the FILSLAN network

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with primary lateral sclerosis (PLS)
* Age over 18 years
* Informed consent signed
* Patients cared in a French ALS centre

Exclusion Criteria

* patients with no oral and written command of the French language
* Patients unable to answer a questionnaire
* Opposition to data processing

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Philippe CORCIA, PR

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Tours

Locations

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University hospital

Brest, , France

Site Status RECRUITING