Systemic Sclerosis' Relatives Reflex

NCT ID: NCT04917146

Last Updated: 2025-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-23

Study Completion Date

2022-06-23

Brief Summary

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Systemic sclerosis (SSc) is a rare, serious disease that is part of chronic inflammatory rheumatism.

It requires multidisciplinary care and a specific therapeutic patient education program.

SSc actually affects every member of the family, the patient as well as those close to him. It deeply affects each member of the family (increased fatigue, stress, social isolation, exhaustion, financial difficulties …) which gives rise to threats of vulnerability and modulates the balance of family relations.

However, there are very few studies on family SSc caregivers. We have raised the question about the experience and needs of caregivers in order to better support them.

The main purpose of this pilot study is to better understand the particularities of relatives (caregivers) of patients suffering from systemic sclerosis and will allow us to refine our knowledge about the assistance they provide for SSc patients and its impact on family caregivers :

* lived experience of the relatives (caregivers);
* physical, mental and socio-professional health of the relatives (caregiver);
* relationship between the relative (caregiver) and the patient.

The research will be carried out at Cochin Hospital, in collaboration with the French Scleroderma Association (ASF).

It will be offered to relatives of SSc patients identified by health team in the rheumatology or internal medicine department, as well as during consultations and patient education activities.

An information note and an informed consent will be given to each patient and his caregiver ; Self-questionnaires will then be offered to relatives.

They can fill them out while they are in the hospital, or at home and return the completed questionnaire.

Caregivers will be questioned about their quality of life, health, relationship with the patient and support situation.

They will also be asked for personal socio-demographic information concerning the patient.

The "caregiver reflex" project is part of the 2020-2022 mobilization and support strategy for caregivers "acting for the health of family caregivers", in which the establishment of a "caregiver reflex" among professionals health is put forward.

Detailed Description

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Exploratory study with family caregivers of patients suffering from Systemic Sclerosis (SSc).

This research work will allow to better understand the experiences and needs of these very particular caregivers, in order to offer them specific educational support and workshops.

It should also allow healthcare teams to develop a "family caregiver reflex", especially in the context of SSc disease to identify and include PAs in PTE programs.

Primary objectives:

Identify caregivers in the SCS patient's family circle: in order to analyze their profile and assess their needs, expectations, projects and difficulties:

* Identify who are the caregivers of SSc people: epidemiological data, profiles of SSc patients followed in rheumatology and Internal medicine departments of Cochin hospital (sex, age, professional activity, possible presence of young people in the entourage, etc.);
* assess the assistance provided by the caregivers: type and specificity;
* Specify the experience and feelings of the caregivers in relation to this aid (positive or negative impact)
* Identify fragile-vulnerable caregivers .

Secondary objectives:

Develop, from this data, educational tools to share with the other members of the FSMR FAI2R and specifically dedicated to the caregivers of SSc patients:

* "Caregiver reflex" tool intended for professionals to better identify and identify caregivers of SSc patients;
* Specific interview guide for the educational diagnosis of caregivers;
* Examples of educational workshops for caregivers meeting identified needs (workshop experienced by the illness of the other, stress management, fatigue, dietary advice, lifestyle, to assist persons in administrative and social procedures...)

Conditions

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Systemic Sclerosis Caregivers

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Caregivers (CG)

Caregivers of patients with systemic Scleroderma

Self-administered questionnaires for relatives (caregivers=CG)

Intervention Type OTHER

Sociodemographic and medical information for the patient and the CG. SF36 questionnaire for the quality of life (physical, mental) of family CGs This assessment will be supplemented by specific questions relating to: physical health, emotional state, personal and leisure activities of the caregiver.

The CG's knowledge and representations of the disease : questions adapted from the Brief-IPQ disease representation questionnaire.

Questions will also focus on the caregiver's reactions to the patient's illness.

We have constructed a questionnaire to assess the main areas of aid in the context of SSc: emotional, domestic help, administrative, medical, for trave (16 items and an open question).

The CG Reaction Assessment-CRA questionnaire to assess the positive and negative dimensions of helping (24 items). It assesses five dimensions: self-esteem, financial impact, impact on health, impact on time and lack of family support.

The reason for the assistance provided.

Interventions

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Self-administered questionnaires for relatives (caregivers=CG)

Sociodemographic and medical information for the patient and the CG. SF36 questionnaire for the quality of life (physical, mental) of family CGs This assessment will be supplemented by specific questions relating to: physical health, emotional state, personal and leisure activities of the caregiver.

The CG's knowledge and representations of the disease : questions adapted from the Brief-IPQ disease representation questionnaire.

Questions will also focus on the caregiver's reactions to the patient's illness.

We have constructed a questionnaire to assess the main areas of aid in the context of SSc: emotional, domestic help, administrative, medical, for trave (16 items and an open question).

The CG Reaction Assessment-CRA questionnaire to assess the positive and negative dimensions of helping (24 items). It assesses five dimensions: self-esteem, financial impact, impact on health, impact on time and lack of family support.

The reason for the assistance provided.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Relatives caregivers of patients suffering from Systemic Scleroderma (family, friends, neighbours);
* Be at least 18 years old;
* Not being the patient's professional caregiver;
* Have signed the informed consent to participate.

Exclusion Criteria

* Inability to answer questionnaires (language, cognitive disorders, etc.).
* under curatorship or tutorship
* with State medical care (AME)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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FSMR FAI2R

UNKNOWN

Sponsor Role collaborator

Ministère des solidarités et de la santé

UNKNOWN

Sponsor Role collaborator

URC-CIC Paris Descartes Necker Cochin

OTHER

Sponsor Role collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Janine-Sophie Giraudet-Le Quintrec, MD

Role: PRINCIPAL_INVESTIGATOR

Cochin Hospital - APHP

Locations

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Rhumatology Service

Paris, , France

Site Status

Countries

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France

References

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Brignon M, Vioulac C, Boujut E, Delannoy C, Beauvais C, Kivits J, Poivret D, Giraudet Le Quintrec JS, Untas A, Rat AC. Patients and relatives coping with inflammatory arthritis: Care teamwork. Health Expect. 2020 Feb;23(1):137-147. doi: 10.1111/hex.12982. Epub 2019 Nov 27.

Reference Type BACKGROUND
PMID: 31774612 (View on PubMed)

Broadbent E, Petrie KJ, Main J, Weinman J. The brief illness perception questionnaire. J Psychosom Res. 2006 Jun;60(6):631-7. doi: 10.1016/j.jpsychores.2005.10.020.

Reference Type BACKGROUND
PMID: 16731240 (View on PubMed)

Brouwer WB, van Exel NJ, van de Berg B, Dinant HJ, Koopmanschap MA, van den Bos GA. Burden of caregiving: evidence of objective burden, subjective burden, and quality of life impacts on informal caregivers of patients with rheumatoid arthritis. Arthritis Rheum. 2004 Aug 15;51(4):570-7. doi: 10.1002/art.20528.

Reference Type BACKGROUND
PMID: 15334429 (View on PubMed)

Canedo-Ayala M, Rice DB, Levis B, Carrier ME, Cumin J, Malcarne VL, Hagedoorn M, Thombs BD; Scleroderma Caregiver Advisory Committee. Factors associated with symptoms of depression among informal caregivers of people with systemic sclerosis: a cross-sectional study. Disabil Rehabil. 2020 Feb;42(3):394-399. doi: 10.1080/09638288.2018.1500647. Epub 2018 Aug 19.

Reference Type BACKGROUND
PMID: 30122129 (View on PubMed)

Given CW, Given B, Stommel M, Collins C, King S, Franklin S. The caregiver reaction assessment (CRA) for caregivers to persons with chronic physical and mental impairments. Res Nurs Health. 1992 Aug;15(4):271-83. doi: 10.1002/nur.4770150406.

Reference Type BACKGROUND
PMID: 1386680 (View on PubMed)

Jacobi CE, van den Berg B, Boshuizen HC, Rupp I, Dinant HJ, van den Bos GA. Dimension-specific burden of caregiving among partners of rheumatoid arthritis patients. Rheumatology (Oxford). 2003 Oct;42(10):1226-33. doi: 10.1093/rheumatology/keg366. Epub 2003 Jun 16.

Reference Type BACKGROUND
PMID: 12810934 (View on PubMed)

Kasle S, Wilhelm MS, Zautra AJ. Rheumatoid arthritis patients' perceptions of mutuality in conversations with spouses/partners and their links with psychological and physical health. Arthritis Rheum. 2008 Jul 15;59(7):921-8. doi: 10.1002/art.23821.

Reference Type BACKGROUND
PMID: 18576302 (View on PubMed)

Lam M, Lehman AJ, Puterman E, DeLongis A. Spouse depression and disease course among persons with rheumatoid arthritis. Arthritis Rheum. 2009 Aug 15;61(8):1011-7. doi: 10.1002/art.24510.

Reference Type BACKGROUND
PMID: 19644902 (View on PubMed)

Leplege A, Ecosse E, Verdier A, Perneger TV. The French SF-36 Health Survey: translation, cultural adaptation and preliminary psychometric evaluation. J Clin Epidemiol. 1998 Nov;51(11):1013-23. doi: 10.1016/s0895-4356(98)00093-6.

Reference Type BACKGROUND
PMID: 9817119 (View on PubMed)

Matheson L, Harcourt D, Hewlett S. 'Your whole life, your whole world, it changes': partners' experiences of living with rheumatoid arthritis. Musculoskeletal Care. 2010 Mar;8(1):46-54. doi: 10.1002/msc.165.

Reference Type BACKGROUND
PMID: 20077577 (View on PubMed)

Rice DB, Canedo-Ayala M, Carboni-Jimenez A, Carrier ME, Cumin J, Malcarne VL, Hagedoorn M, Thombs BD; Scleroderma Caregiver Advisory Team. Challenges and support service preferences of informal caregivers of people with systemic sclerosis: a cross-sectional survey. Disabil Rehabil. 2020 Aug;42(16):2304-2310. doi: 10.1080/09638288.2018.1557268. Epub 2019 Jan 29.

Reference Type BACKGROUND
PMID: 30696293 (View on PubMed)

Untas A, Vioulac C, Boujut E, Delannoy C, Poivret D, Rat AC, Beauvais C, Giraudet Le Quintrec JS. What Is Relatives' Role in Arthritis Management? A Qualitative Study of the Perceptions of Patient-Relative Dyads. Patient Prefer Adherence. 2020 Jan 7;14:45-53. doi: 10.2147/PPA.S231919. eCollection 2020.

Reference Type BACKGROUND
PMID: 32021116 (View on PubMed)

Other Identifiers

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APHP210756

Identifier Type: -

Identifier Source: org_study_id

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