Novel Neuroradiological Workflow for the Assisted DIAgnosis and Management of DEMentia with Artificial Intelligence
NCT ID: NCT06877182
Last Updated: 2025-03-19
Study Results
Results pending
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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Recruitment Status
ACTIVE_NOT_RECRUITING
Total Enrollment
80000 participants
Study Classification
OBSERVATIONAL
Study Start Date
2024-08-30
Study Completion Date
2027-08-31
Brief Summary
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Identifying, screening and monitoring individuals at risk of Alzheimer's disease (AD) and dementia is a formidable challenge. Neuroimaging, and in particular magnetic resonance imaging (MRI), is crucial to detect structural neurodegeneration. However, current quantification tools are mainly limited to research contexts and produce non-standardised results. DIADEMA will build a systematic and standardised workflow to support neuro(radio)logical diagnosis. By combining artificial intelligence (AI) and machine learning (ML) the investigators will significantly enhance the clinical diagnosis of AD in neuroradiology. The investigator's main hypothesis is that an efficient workflow and associated higher diagnostic accuracy will substantially reduce healthcare costs, support clinical decision-making, provide second-opinion tools and improve patient care. This dual advance will have a profound impact on the healthcare system, marking an important step in the fight against Alzheimer's disease and dementia.
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Detailed Description
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Conditions
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Alzheimer Disease
Dementia
Study Design
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Observational Model Type
COHORT
Study Time Perspective
RETROSPECTIVE
Interventions
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Magnetic Resonance Imaging with Contrast
To evaluate the possibility to improve the neuroradiologic workflow with AI models
Intervention Type
DIAGNOSTIC_TEST
Eligibility Criteria
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Inclusion Criteria
* patients who perform brain magnetic resonance during the last 20 years
Exclusion Criteria
\-
Eligible Sex
ALL
Accepts Healthy Volunteers
No
Sponsors
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UNINA
UNKNOWN
Sponsor Role
collaborator
UNITO
UNKNOWN
Sponsor Role
collaborator
Ospedale Fate bene Fratelli di Brescia
UNKNOWN
Sponsor Role
collaborator
IRCCS SYNLAB SDN
OTHER
Sponsor Role
lead
Responsible Party
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Responsibility Role
SPONSOR
Principal Investigators
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Marco Aiello
Role: PRINCIPAL_INVESTIGATOR
IRCCS SYNLAB SDN
Locations
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Irccs Synlab Sdn
Naples, , Italy
Site Status
Countries
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Italy
References
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Other Identifiers
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1/24
Identifier Type: -
Identifier Source: org_study_id
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