Unexplained Recurrent Pregnancy Loss: New Therapeutic Perspectives

NCT ID: NCT06867900

Last Updated: 2025-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-01

Study Completion Date

2025-07-06

Brief Summary

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Evaluation of gut permeability and endometrial inflammasome NLRP3 in women with unexplaid recurrent pregnancy loss before-after administration of Bifidobacteriumlongum ES1.

Detailed Description

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Conditions

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Miscarriage, Recurrent

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Bifidobacterium Longum

Group Type EXPERIMENTAL

Bifidobacterium Longum ES1

Intervention Type DIETARY_SUPPLEMENT

Oral administration of Bifidobacterium Longum ES1 for three months.

Interventions

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Bifidobacterium Longum ES1

Oral administration of Bifidobacterium Longum ES1 for three months.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Idiopathic recurrent pregnancy loss
* Genetic predisposition to celiac disease

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Chiara Tersigni

Role: PRINCIPAL_INVESTIGATOR

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Locations

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Reasearch Laboratory 3J IRCCS Gemelli

Rome, , Italy

Site Status

Countries

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Italy

Other Identifiers

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1355

Identifier Type: -

Identifier Source: org_study_id

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