The Beijing Longitudinal Disability Survey in Community Elderly

NCT ID: NCT06863727

Last Updated: 2025-03-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1962 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-08-07

Study Completion Date

2028-07-31

Brief Summary

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The goal of this observational study is to establish the prospective cohort of the Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE) to explore the high-risk factors and preventive interventions for disability and cognitive impairment among community-dwelling adults aged 65 years and over. The main question it aims to answer is:

* What are the high-risk factors able to predict the incidence and advance of disability and cognitive impairment in community-dwelling adults aged 65 years and over?
* What are the categories of function and cognitive performance trajectory in community-dwelling adults aged 65 years and over?

Detailed Description

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BLINDSCE is a community-based prospective cohort study that includes individuals aged 65 and over from urban and rural areas in Beijing. Participants will provide detailed demographic information and undergo multifactorial questionnaires, disability measurements, cognitive assessments, other disability-related outcomes, and clinical biochemical measures. The study has started recruitment and enrollment in 2023 and will follow-up once every 1-2 year. This work consists of three steps as follows. First, by collecting baseline and follow-up data of participants, we plan to establish a community-dwelling elderly database in Beijing. Second, high-risk factors can be pre-screening based on this cross-sectional analysis. Third, longitudinal data was used to develop the prediction model and trajectory analysis for disability and cognitive impairment.

Conditions

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Ageing Disability Cognitive Impairment Frailty Intrinsic Capacity

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Community-dwelling adults aged 65 years or older who reside in Beijing.
* Participants who sign an institutionally approved informed consent.

Exclusion Criteria

* Participants with severe mental disorders and serious medical conditions preventing study investigation
* Participants undergoing long-term professional treatment for physical function and cognitive functioning, such as hospitalization or rehabilitation.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Beijing Municipal Health Commission

OTHER_GOV

Sponsor Role collaborator

Xuanwu Hospital, Beijing

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yansu Guo, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Beijing Geriatric Healthcare and Disease Prevention Center, Xuanwu Hospital, Capital Medical University

Locations

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Xuanwu Hospital, Capital Medical University

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yansu Guo, Ph.D

Role: CONTACT

0086031183973736

Facility Contacts

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Yansu Guo, Ph.D

Role: primary

0086031183973736

References

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Cheng S, Du X, Hou C, Liu H, Lei S, Wu Y, Yue X, Guo Y. Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE): protocol for a community-based prospective longitudinal cohort study about disability prediction model. BMJ Open. 2025 May 15;15(5):e091955. doi: 10.1136/bmjopen-2024-091955.

Reference Type DERIVED
PMID: 40379348 (View on PubMed)

Other Identifiers

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2024-2G-20112

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

No.[2023]129

Identifier Type: -

Identifier Source: org_study_id

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