Assessment of Biological and Biometrological Parameters in Adult Subjects with Androgenetic Alopecia

NCT ID: NCT06854432

Last Updated: 2025-03-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

46 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-05

Study Completion Date

2024-04-25

Brief Summary

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Androgenetic alopecia is a chronic pathology affecting approximately 50% of men at 50 years old and is characterized by a progressive miniaturization of the hair follicle leading to a localized baldness.

Although it has been shown that testosterone metabolism plays a central role in this pathology, targeting this biological pathway is not fully efficient to treat androgenetic alopecia, suggesting that other factors are involved, notably factors linked to the perifollicular environment. Moreover, the very specific pattern of androgenetic alopecia is not yet fully understood: the occipital and lower temporal areas of the scalp are always preserved. Once the hair follicle has disappeared, it is not possible to make it grow back, it is then important to provide a treatment that slows down the progression of androgenetic alopecia at the earliest stage of the pathology, and that specifically targets the affected area.

The aim of this study is to better understand androgenetic alopecia pathophysiology by a multi-omic approaches and biometrological analysis, in the same study, on the local ecosystem of bald scalp areas and non-bald scalp areas of adult with androgenetic alopecia, compared to scalp of adult without androgenetic alopecia.

Detailed Description

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Conditions

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Alopecia, Androgenetic Healthy

Study Design

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Allocation Method

NA

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Control subject group

Group Type OTHER

Biometrological measurements

Intervention Type OTHER

Measurements will be taken from the scalp: on the vertex and occiput areas.

Biological sampling

Intervention Type OTHER

Samples will be taken from the scalp: on the vertex and occiput areas.

Subject group with androgenetic alopecia

Group Type OTHER

Biometrological measurements

Intervention Type OTHER

Measurements will be taken from the scalp: on the vertex and occiput areas.

Biological sampling

Intervention Type OTHER

Samples will be taken from the scalp: on the vertex and occiput areas.

Interventions

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Biometrological measurements

Measurements will be taken from the scalp: on the vertex and occiput areas.

Intervention Type OTHER

Biological sampling

Samples will be taken from the scalp: on the vertex and occiput areas.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Criteria related to the population:

* Subject having received on study areas artificial UV exposure, excessive or prolonged exposure to natural sunlight between selection and inclusion visit

Criteria related to the disease:

• Subject with any adverse event occurring between selection and inclusion visit liable to interfere with the study assessments

Criteria related to treatments and/or products:

• Any procedures, treatments, products and/or hair care taken, applied or performed between selection and inclusion visit liable to interfere with the study assessments
Minimum Eligible Age

30 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Pierre Fabre Dermo Cosmetique

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Skin Research Center

Toulouse, , France

Site Status

Countries

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France

Other Identifiers

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INTERALOPECIE

Identifier Type: -

Identifier Source: org_study_id

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