Thulium Laser and Growth Factors for Androgenetic Alopecia

NCT ID: NCT07079657

Last Updated: 2025-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-01

Study Completion Date

2025-10-01

Brief Summary

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Androgenetic alopecia (AGA) is a common cause of hair loss worldwide. It mainly affects the frontal and parietal regions of the scalp in up to 70 % of men and 40 % of women and has a significant negative psychological and emotional impact on those affected.

Various therapies are currently approved for the treatment of AGA in men and women, including topical minoxidil, topical or systemic finasteride, platelet-rich plasma and hair transplantation. In addition to these pharmacological and surgical interventions, laser therapies including thulium laser with growth factors have gained popularity.

Despite the clinical use of the thulium laser with growth factors in combination with LED phototherapy, there are only a few studies to date that have adequately investigated the objective and patient-side benefits of this therapy.

Detailed Description

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Conditions

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Androgenetic Alopecia (AGA)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Thulium laser + growth factor serum + LED

Thulium laser + growth factor serum + LED

Group Type ACTIVE_COMPARATOR

Thulium laser + growth factor serum + LED

Intervention Type PROCEDURE

3 sessions at intervals of 6 weeks

Thulium laser + growth factor serum

Thulium laser + growth factor serum

Group Type ACTIVE_COMPARATOR

Thulium laser + growth factor serum

Intervention Type PROCEDURE

3 sessions at intervals of 6 weeks

Thulium laser

Thulium laser

Group Type ACTIVE_COMPARATOR

Thulium laser

Intervention Type PROCEDURE

3 sessions at intervals of 6 weeks

Interventions

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Thulium laser + growth factor serum + LED

3 sessions at intervals of 6 weeks

Intervention Type PROCEDURE

Thulium laser + growth factor serum

3 sessions at intervals of 6 weeks

Intervention Type PROCEDURE

Thulium laser

3 sessions at intervals of 6 weeks

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Men and women aged 18 and over
* Good general health, no relevant previous illnesses
* Presence of an AGA
* Cognitive ability and willingness to give consent (informed consent)
* Be willing and able to attend follow-up visits

Exclusion Criteria

* Age \< 18 years
* Pregnant or breastfeeding women
* Scarring alopecia, alopecia due to dermatoses (e.g. lichen ruber, lupus erythemodes,...), alopecia due to chemical or physical noxae, and other non-AGAs
* Significant scarring of the region to be treated
* Significant open wounds or lesions in the region to be treated
* Metallic implants in the head region
* Mental illnesses (psychoses, body perception disorders)
* Use of isotretinoin or other retinoids, psychotropic drugs, coumarins or heparins in the last 2 weeks
* Resurfacing (fractional, ablative, non-ablative) of the affected region \< 2 months before and during the study period
* Tendency to excessive scarring
* Lack of informed consent and/or data protection declarations
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universitätsklinikum Hamburg-Eppendorf

OTHER

Sponsor Role lead

Responsible Party

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Lynhda Nguyen

Dr. med.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University Medical Center Hamburg-Eppendorf

Hamburg, City state of Hamburg, Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Lynhda Nguyen, Dr. med.

Role: CONTACT

+49 (0)40 7410 54289

Facility Contacts

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Lynhda Nguyen, Dr. med.

Role: primary

+49 (0)40 7410 54289

Other Identifiers

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04-23

Identifier Type: -

Identifier Source: org_study_id

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