Prevention Ambassadors: Intervention to Promote HIV Service Engagement in the Networks of SSP Clients

NCT ID: NCT06848686

Last Updated: 2026-01-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

210 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-03

Study Completion Date

2027-02-28

Brief Summary

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HIV testing and service uptake are infrequent among people who use drugs (PWUD) in the United States. In partnership with a community-based syringe service program (SSP), this project will develop the SSP-based "Prevention Ambassadors" (PA) intervention to promote HIV testing and service uptake among PWUD via the secondary distribution (i.e., peer delivery) of HIV self-testing (HIVST) kits with local HIV service information and referrals to HIV service navigation in the social networks of SSP clients (i.e., PWUD). The PA intervention will then be piloted to assess its preliminary effects, acceptability, and feasibility among PWUD in the Ending the HIV Epidemic priority jurisdiction of Riverside County, California.

Detailed Description

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Conditions

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HIV

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Investigators

Study Groups

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Prevention Ambassadors

Group Type EXPERIMENTAL

Prevention Ambassadors

Intervention Type BEHAVIORAL

Delivery of prevention supplies and information on local services plus training to build the capacity of PWUD to distribute HIV self-testing (HIVST) kits with information and referrals to other PWUD in their social networks to promote HIV testing and HIV service engagement among PWUD.

SSP Standard of Care

Group Type OTHER

SSP Standard of Care

Intervention Type BEHAVIORAL

Delivery of prevention supplies and information on local services.

Interventions

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Prevention Ambassadors

Delivery of prevention supplies and information on local services plus training to build the capacity of PWUD to distribute HIV self-testing (HIVST) kits with information and referrals to other PWUD in their social networks to promote HIV testing and HIV service engagement among PWUD.

Intervention Type BEHAVIORAL

SSP Standard of Care

Delivery of prevention supplies and information on local services.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Being greater than or equal to 18 years old
* Reporting drug use (past month)
* Having other people who use drugs (PWUD) in one's social network
* Being willing to talk about HIV testing and services with at least 2 PWUD in their networks and attempt to refer them to the study
* Speaking English fluently


* Being greater than or equal to 18 years old
* Reporting drug use (past 3 months)
* Being recruited by an index participant (evidenced by presenting the coupon used to recruit them)
* Speaking English fluently

Exclusion Criteria

\- Persons who participated in formative study activities related to the development of the PA intervention will not be eligible to participate.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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San Diego State University

OTHER

Sponsor Role lead

University of California, San Diego

OTHER

Sponsor Role collaborator

University of California, Riverside

OTHER

Sponsor Role collaborator

Dap Health

OTHER

Sponsor Role collaborator

National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role collaborator

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Heather A Pines

Role: PRINCIPAL_INVESTIGATOR

San Diego State University

Angela R Bazzi

Role: PRINCIPAL_INVESTIGATOR

University of California, San Diego

Locations

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San Diego State University

San Diego, California, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Heather Pines

Role: CONTACT

619-594-2481

Facility Contacts

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Heather Pines

Role: primary

619-594-2481

Other Identifiers

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R34DA058389

Identifier Type: NIH

Identifier Source: secondary_id

View Link

HS-2023-0051

Identifier Type: -

Identifier Source: org_study_id

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