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The Impact of Dental Health on Complications During and Following Radiotherapy in the Head and Neck Region.

NCT ID: NCT06840639

Last Updated: 2025-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

750 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-01

Study Completion Date

2025-01-01

Brief Summary

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Study the risk of complications after dental extractions in patients recieving radiotherapy.

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Detailed Description

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Dental extractions before radiotherapy in the head and neck region is an established part of the treatment plan for patients with malignant disease. There are contradictory results in the literature regarding the importance timing and magnitude of extractions. It is important to minimize complications in this patient group since the regular therapy is already detrimental to the affected tissues. Patients were extracted from the ARTSCAN register were the population was followed for 4 years for several factors, including development of osteoradionecrosis. The aim is to evaluate which diagnoses are more prone to develop complications after extraction. If there is a relationship between occurrence of complication and magnitude of dental pathology.

Conditions

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Head and Neck Neoplasms Radiotherapy; Complications Extracting Own Teeth

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

OTHER

Study Groups

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Dental extractions with complications

patients recieving dental extractions and developing osteoradionecrosis

Dentoalveolar surgery

Intervention Type PROCEDURE

Surgery to extract teeth

Dental extractions without complications

patients recieving dental extractions and not developing osteoradionecrosis

No interventions assigned to this group

Interventions

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Dentoalveolar surgery

Surgery to extract teeth

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Malignant diagnosis
* radiotherapy pre or postoperative

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Lund University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Philip Fransson, Msc

Role: PRINCIPAL_INVESTIGATOR

Lund University Hospital

Locations

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Oral and Maxillofacial department

Lund, Skåne County, Sweden

Site Status

Countries

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Sweden

Other Identifiers

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LundUH2

Identifier Type: -

Identifier Source: org_study_id

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