Positive Psychological Intervention for Parkinson's Disease Patients

NCT ID: NCT06832358

Last Updated: 2025-02-18

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-02-01
• Study Completion Date: 2023-04-01

Brief Summary

This study aims to evaluate the impact of positive psychological intervention based on the PERMA model on Parkinson's disease patients by assessing their depression, quality of life, and related psychological indicators before and after intervention.

Conditions

Parkinson

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Study group

The study group was treated with routine nursing combined with PERMA positive psychological intervention mode

Group Type: EXPERIMENTAL

Routine nursing methods

Intervention Type: BEHAVIORAL

According to their condition, they receive individualized drug treatment, including the main drugs of Parkinson's disease (such as dopamine replacement drugs) and combined antidepressant drugs. Secondly, regular follow-up evaluations will be conducted to monitor disease progression and drug side effects. At the same time, patients and their families will receive health education on Parkinson's disease and depression.The patients would receive basic psychological support. Medical staff will encourage patients to express their emotions and pay attention to their psychological state, which will help alleviate anxiety and depression. Medical staff will provide patients with information about local support organizations and social groups, and encourage patients to participate in related activities to increase social interaction and emotional support.

PERMA positive psychological intervention mode

Intervention Type: BEHAVIORAL

(1) Formation of an intervention team.(2) Development and execution of interventions.The study group participated in a series of positive psychology workshop involving interviews and exercises aligned with the PERMA model as part of their routine health education. Each participant took part in individualized interviews focused on two specific topics each week until all subjects were covered, with each session lasting between 30 to 50 minutes. This interview phase continued for one month, conducted in the hospital ward.

Control group

The control group will receive routine nursing methods to ensure that patients receive standard medical support and treatment during the intervention period.

Group Type: ACTIVE_COMPARATOR

Routine nursing methods

Intervention Type: BEHAVIORAL

According to their condition, they receive individualized drug treatment, including the main drugs of Parkinson's disease (such as dopamine replacement drugs) and combined antidepressant drugs. Secondly, regular follow-up evaluations will be conducted to monitor disease progression and drug side effects. At the same time, patients and their families will receive health education on Parkinson's disease and depression.The patients would receive basic psychological support. Medical staff will encourage patients to express their emotions and pay attention to their psychological state, which will help alleviate anxiety and depression. Medical staff will provide patients with information about local support organizations and social groups, and encourage patients to participate in related activities to increase social interaction and emotional support.

Interventions

Routine nursing methods

According to their condition, they receive individualized drug treatment, including the main drugs of Parkinson's disease (such as dopamine replacement drugs) and combined antidepressant drugs. Secondly, regular follow-up evaluations will be conducted to monitor disease progression and drug side effects. At the same time, patients and their families will receive health education on Parkinson's disease and depression.The patients would receive basic psychological support. Medical staff will encourage patients to express their emotions and pay attention to their psychological state, which will help alleviate anxiety and depression. Medical staff will provide patients with information about local support organizations and social groups, and encourage patients to participate in related activities to increase social interaction and emotional support.

Intervention Type: BEHAVIORAL

PERMA positive psychological intervention mode

(1) Formation of an intervention team.(2) Development and execution of interventions.The study group participated in a series of positive psychology workshop involving interviews and exercises aligned with the PERMA model as part of their routine health education. Each participant took part in individualized interviews focused on two specific topics each week until all subjects were covered, with each session lasting between 30 to 50 minutes. This interview phase continued for one month, conducted in the hospital ward.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Subjects must meet the clinical diagnostic criteria for primary Parkinson's disease
• Subjects must not have a history of depression or other significant illnesses (e.g., stroke, coronary heart and tumor disease)
• Subjects should have clear consciousness, effective communication capabilities, and basic comprehension and reading skills to complete routine assessments
• The diagnosis of depression adhered to the ' Chinese Classification and Diagnostic Criteria for Mental Disorders ' (Revised Third Edition)
• Subjectsshould not have schizophrenia
• Subjects should not have substance abuse (alcohol, tobacco or other psychoactive substances)

Exclusion Criteria

• Subjects with significant mental or cognitive impairment that communication or completion of scale assessments
• Subjects exhibiting severe self-harm or suicidal tendencies
• Subjects with severe dysfunction of the heart, liver, kidney or other critical organs
• Subjects with contraindications for transcranial magnetic stimulation (such as cochlear implant, pacemaker, built-in pump, artificial metal heart valve, suspected metal in the eye or elevated intracranial pressure)
• Subjects with a history of epilepsy that is poorly controlled
• Subjects with Parkinson's disease who have undergone surgical treatment

• Minimum Eligible Age: 42 Years
• Maximum Eligible Age: 81 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

First Affiliated Hospital of Wenzhou Medical University

OTHER

Sponsor Role: lead

Responsible Party

Meichun Shu

Doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

The First Affiliated Hospital of Wenzhou Medical University

Wenzhou, , China

Countries

China

Other Identifiers

Meichun Shu2

Identifier Type: -

Identifier Source: org_study_id