Comparison of Endometrial Protein Profile in Spontaneous Versus Stimulated Menstrual Cycles in Poor Responders

NCT ID: NCT06804174

Last Updated: 2025-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-01

Study Completion Date

2024-09-01

Brief Summary

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Evaluation of endometrial protein profile in spontaneous and stimulated menstrual cycles

Detailed Description

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Conditions

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Proteome

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Poor responder women as per POSEIDON criteria

Group Type EXPERIMENTAL

use of gonadotropins

Intervention Type OTHER

Comparison of endometrial proteome during the window of implantation between stimulated and spontaneous cycles.

Interventions

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use of gonadotropins

Comparison of endometrial proteome during the window of implantation between stimulated and spontaneous cycles.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Primary infertility
2. Poor ovarian response

Exclusion Criteria

1. Normal or high ovarian response to gonadotropin stimulation
2. Menstrual cycle disorders
3. Severe male cause of infertility
4. Preimplantation genetic testing
5. Pathological findings of the uterus (fibroids, endometrial polyps, adenomyosis) and fallopian tubes (distal occlusion of one or both fallopian tubes with hydrosalpinx).
Minimum Eligible Age

18 Years

Maximum Eligible Age

43 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Slovenian Research Agency (ARRS)

UNKNOWN

Sponsor Role collaborator

University Medical Centre Ljubljana

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Eda Prof. Vrtačnik bokal, MD, PhD

Role: STUDY_CHAIR

Division of Obstetrics and Gynecology, University Medical Centre Ljubljana

Locations

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Division of Obstetrics and Gynecology, university Medical Centre Ljubljana

Ljubljana, , Slovenia

Site Status

Countries

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Slovenia

Other Identifiers

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(0120-319/2021/3)

Identifier Type: -

Identifier Source: org_study_id

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