Clinical Application of Carbon Nanoparticles in Lymph Node Tracing and Surgery Guiding of Colorectal Cancer

NCT ID: NCT06783985

Last Updated: 2025-01-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

146 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-03-16

Study Completion Date

2024-04-20

Brief Summary

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This trial aims to clarify the relationship between carbon nanoparticles labeled lymph nodes and lymph node metastasis in different lymph node regions of colorectal cancer, and to clarify the application value of carbon nanoparticles in lymph node dissection in colorectal cancer surgery.

Detailed Description

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Conditions

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Colorectal Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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CNP group

Every patient received endoscopic injection of 0.5 ml CNP suspension (Chongqing LUMMY Pharmaceutical Co., Chongqing, China) into submucosal layer at one point, at the lower margin of the tumor. All patients subsequently underwent laparoscopic or robotic radical resection with D3 LN dissection. Tumor tissue and LNs s were isolated from surgical specimen by the same pathologist. LNs dissection and harvest were on the basis of the Japanese classification of colorectal carcinoma.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. a diagnosis of colorectal cancer;
2. endoscopic injection of CNP suspension preoperatively
3. planned radical resection of colorectal cancer
4. older than 18 years of age

Exclusion Criteria

(a) emergency surgery;
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sir Run Run Shaw Hospital

OTHER

Sponsor Role lead

Responsible Party

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Bingjun Bai

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sir Run Run Shaw hospital

Hangzhou, Zhejiang, China

Site Status

Countries

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China

Other Identifiers

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SirRRSH-CNP-CRC

Identifier Type: -

Identifier Source: org_study_id

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