Integrating Cognitive Assessments Into the Heat Tolerance Test After Exertional Heat Injury

NCT ID: NCT06764264

Last Updated: 2025-01-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-02-01

Study Completion Date

2024-12-21

Brief Summary

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This prospective observational study is to evaluate soldiers post-exertional heat injury (EHI) during a heat tolerant test (HTT) to investigate the impact on their cognitive performance.

Detailed Description

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The objective of the proposed research is to add a cognitive evaluation to the physiological parameters monitored in the heat tolerance test (HTT) and to construct a new cognitive-physiological model for evaluation based on the accumulated knowledge on soldiers' heat tolerance. Each year, in the Israel Defense Forces (IDF), approximately 50 soldiers post exertional heat injury (EHI) are referred to perform the HTT. The HTT is carried out approximately one month post injury as part of clinical evaluation of the patient and is also intended to determine return to duty for combatants in field units. Currently, the criteria used in the HTT to determine heat tolerance are based solely on physiological parameters, while no cognitive evaluation is utilized in the HTT. Noteworthy are the numerous studies published in scientific literature describing the influence of exposure to heat conditions and physical effort on cognition and psychological strain in humans.

The subjects performing the HTT will also undergo cognitive evaluation and psychological strain assessment using tests used and validated in the research laboratories of the United States military (USARIEM). The cognitive evaluation will be performed in addition to the validated physiological monitoring performed in the HTT. All gathered physiological and cognitive data will be used to construct new bio-statistical models and new criteria will be suggested for the definition of heat tolerance or intolerance.

Conditions

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Exertional Heat Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Combat soldiers post exertional heat injury

Participants were classified into heat-intolerant (HI) or heat-tolerant (HT) groups based on their HTT physiological outcomes.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Combat soldiers post exertional heat injury

Exclusion Criteria

* Additional medical condition restricting combat duty
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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The Chaim Sheba Medical Center

OTHER

Sponsor Role collaborator

Medical Corps, Israel Defense Force

OTHER

Sponsor Role lead

Responsible Party

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ITAY

Dr. Sagi Shpitzer, MD, Chief Medical Officer, IDF Physiology Institute, Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Daniel S Moran, PhD

Role: STUDY_DIRECTOR

Institute of Military Physiology, IDF Medical Corps, Tel Hashomer, Israel

Locations

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Heller Institute, Institute of Military Physiology, IDF Medical Corps

Tel Litwinsky, Israel, Israel

Site Status

Countries

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Israel

References

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Moran DS, Shitzer A, Pandolf KB. A physiological strain index to evaluate heat stress. Am J Physiol. 1998 Jul;275(1):R129-34. doi: 10.1152/ajpregu.1998.275.1.R129.

Reference Type BACKGROUND
PMID: 9688970 (View on PubMed)

Epstein Y, Sohar E, Shapiro Y. Exertional heatstroke: a preventable condition. Isr J Med Sci. 1995 Jul;31(7):454-62.

Reference Type BACKGROUND
PMID: 7607879 (View on PubMed)

Moran DS, Heled Y, Still L, Laor A, Shapiro Y. Assessment of heat tolerance for post exertional heat stroke individuals. Med Sci Monit. 2004 Jun;10(6):CR252-7. Epub 2004 Jun 1.

Reference Type BACKGROUND
PMID: 15173669 (View on PubMed)

Moran DS, Erlich T, Epstein Y. The heat tolerance test: an efficient screening tool for evaluating susceptibility to heat. J Sport Rehabil. 2007 Aug;16(3):215-21. doi: 10.1123/jsr.16.3.215.

Reference Type BACKGROUND
PMID: 17923727 (View on PubMed)

Other Identifiers

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IDF- 123 1779-2017

Identifier Type: -

Identifier Source: org_study_id

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