Risk Factors for Exertional Heat Illness

NCT ID: NCT04979455

Last Updated: 2025-03-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

783 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-11

Study Completion Date

2025-07-31

Brief Summary

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The arduous nature of military training and operations require personnel to encounter high heat load, e.g., during intense physical exertion, particularly in the heat. These conditions reduce operational effectiveness and expose personnel to a risk of incapacitation and death from exertional heat illness (EHI).

The aim of this study is to examine traditional and novel risk factors that may increase thermal strain and EHI likelihood in military recruits undergoing strenuous physical exercise.

Detailed Description

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Conditions

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Exertional Heat Illness

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Exertional heat illness

Participants who experience an atypical elevation in thermal strain or an EHI undergoing strenuous physical exercise.

Core temperature monitoring

Intervention Type OTHER

Core temperature will be monitored on the day of exercise

Questionnaires

Intervention Type BEHAVIORAL

Questionnaires will be completed at baseline and on the day of exercise

Heart rate monitoring

Intervention Type OTHER

Heart rate will be monitored on the day of exercise

Urine collection

Intervention Type OTHER

Urine samples will be collected at baseline and on the day of exercise

Sleep monitoring

Intervention Type OTHER

Sleep will be monitored at baseline and on the day of exercise

Blood collection

Intervention Type OTHER

Blood samples will be completed at baseline

Saliva collection

Intervention Type OTHER

Saliva samples will be collected at baseline and on the day of exercise

Throat swab collection

Intervention Type OTHER

Throat swab samples will be collected at baseline and on the day of exercise

Stool collection

Intervention Type OTHER

Stool samples will be collected at baseline and on the day of exercise

Control

Participants who do not experience an atypical elevation in thermal strain or an EHI undergoing strenuous physical exercise.

Core temperature monitoring

Intervention Type OTHER

Core temperature will be monitored on the day of exercise

Questionnaires

Intervention Type BEHAVIORAL

Questionnaires will be completed at baseline and on the day of exercise

Heart rate monitoring

Intervention Type OTHER

Heart rate will be monitored on the day of exercise

Urine collection

Intervention Type OTHER

Urine samples will be collected at baseline and on the day of exercise

Sleep monitoring

Intervention Type OTHER

Sleep will be monitored at baseline and on the day of exercise

Blood collection

Intervention Type OTHER

Blood samples will be completed at baseline

Saliva collection

Intervention Type OTHER

Saliva samples will be collected at baseline and on the day of exercise

Throat swab collection

Intervention Type OTHER

Throat swab samples will be collected at baseline and on the day of exercise

Stool collection

Intervention Type OTHER

Stool samples will be collected at baseline and on the day of exercise

Interventions

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Core temperature monitoring

Core temperature will be monitored on the day of exercise

Intervention Type OTHER

Questionnaires

Questionnaires will be completed at baseline and on the day of exercise

Intervention Type BEHAVIORAL

Heart rate monitoring

Heart rate will be monitored on the day of exercise

Intervention Type OTHER

Urine collection

Urine samples will be collected at baseline and on the day of exercise

Intervention Type OTHER

Sleep monitoring

Sleep will be monitored at baseline and on the day of exercise

Intervention Type OTHER

Blood collection

Blood samples will be completed at baseline

Intervention Type OTHER

Saliva collection

Saliva samples will be collected at baseline and on the day of exercise

Intervention Type OTHER

Throat swab collection

Throat swab samples will be collected at baseline and on the day of exercise

Intervention Type OTHER

Stool collection

Stool samples will be collected at baseline and on the day of exercise

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Men and women aged 17-35 years enrolled in military training

Exclusion Criteria

* Self-report as pregnant
Minimum Eligible Age

17 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Institute of Naval Medicine (UK)

UNKNOWN

Sponsor Role collaborator

CTCRM Lympstone (UK)

UNKNOWN

Sponsor Role collaborator

University of Portsmouth (UK)

UNKNOWN

Sponsor Role collaborator

Public Health Wales

OTHER_GOV

Sponsor Role collaborator

Bangor University (UK)

UNKNOWN

Sponsor Role collaborator

Headquarters Army Recruiting and Initial Training Command (UK)

UNKNOWN

Sponsor Role collaborator

Defence Science and Technology (UK)

UNKNOWN

Sponsor Role collaborator

Liverpool John Moores University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Commando Training Centre Royal Marine

Lympstone, Devon, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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2029/MODREC/21

Identifier Type: -

Identifier Source: org_study_id

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