A Pilot Study of a Remote ADHD Monitoring Program

NCT ID: NCT06743425

Last Updated: 2025-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

36 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-04

Study Completion Date

2026-07-01

Brief Summary

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RAMP is a pilot study examining the use of an Attention-Deficit/Hyperactivity Disorder (ADHD) Monitoring Program during the early stages of treating ADHD in children living in rural settings. This trial will enroll 36 caregiver/infant dyads across 2 sites and will evaluate feasibility endpoints rather than clinical outcomes. Enrolled participants will be randomized 1:1 to the intervention group (RAMP reports) or control group (digital education handouts). The study duration is 10 months, including start-up, enrollment and intervention, and data analysis and manuscript submission.

Detailed Description

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The RAMP study is designed to examine the use of an attention-Deficit/Hyperactivity Disorder (ADHD) Monitoring Program during the early stages of treating ADHD in children living in rural settings. It is a multi-site pilot study conducted across two Institutional Development Award (IDeA) States Pediatric Clinical Trials Network (ISPCTN) sites in conjunction with four practices with high rural and/or underserved populations.

The Remote ADHD Monitoring Program (RAMP) will include provider ADHD Best Practice education, caregiver and teacher prompts for frequent RAMP Reports of inattention and hyperactivity symptoms and a provider dashboard with enrolled children. The RAMP Report includes the publicly available Vanderbilt Rating Scales (henceforth shortened to Vanderbilt Assessment), which is a commonly used, guideline-recommended tool for both diagnosis and management of ADHD for use by parents and teachers.

Families will be approached until 36 caregiver/child dyads are enrolled. Those enrolled will be randomized 1:1 to either the intervention group or control group. The intervention group will be enrolled in the RAMP, with prompts to provide frequent reports including ADHD symptoms. The control group will provide ADHD symptom reports through paper forms (usual care), on a provider determined schedule.

The intervention group will be enrolled in the RAMP platform and will receive text-based requests for reports with embedded links to fill out the RAMP questionnaires weekly for 4 weeks, then monthly for 2 months. The control group will receive digital education handouts about age-appropriate pediatric health topics weekly for 4 weeks, then monthly for 2 months.

For the intervention group, the child's teacher can voluntarily return the RAMP questionnaires as well, but will not have direct contact with the study team. The child's provider will also be a participant for the intervention group, and will receive requests to review the submitted RAMP reports.

The primary endpoint for this study is to evaluate the number of clinical assessments per participant that are completed by caregivers and teacher and returned to providers for ADHD management.

The secondary endpoint for this study is to evaluate the proportion of all submitted RAMP reports that are reviewed by providers.

The results of this pilot will be used to design a full-scale efficacy trial in additional rural sites to expand diversity and assess generalizability.

Conditions

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Attention-deficit/Hyperactivity Disorder ADHD

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This is a multi-center, parallel, unblinded, randomized controlled clinical trial.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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RAMP Reports

Submit RAMP reports weekly for 4 weeks and then monthly for 2 months.

Group Type EXPERIMENTAL

RAMP Reports

Intervention Type OTHER

Participants will receive text-based requests for reports with embedded links to select radio button questionnaires directly on their mobile device. Questions include current inattention/hyperactivity symptoms, school performance, and any engagement in behavioral therapy. Inattention/hyperactivity symptom questions and scoring is taken directly from the publicly available Vanderbilt Rating Scales, which is a commonly used, guideline-recommended tool for both diagnosis and management of ADHD for use by parents and teachers.

Digital Education Handouts

Standard of care determined by the treating healthcare provider and digital education handouts (attention controls) distributed by the study team weekly for 4 weeks and then monthly for 2 months.

Group Type ACTIVE_COMPARATOR

Digital Education Handouts

Intervention Type OTHER

The digital education handouts will be sent via email to the control group and will serve as an attention control. They will consist of information regarding a general pediatric health topic and will be emailed at intervals matching the RAMP requests in the intervention group.

Interventions

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RAMP Reports

Participants will receive text-based requests for reports with embedded links to select radio button questionnaires directly on their mobile device. Questions include current inattention/hyperactivity symptoms, school performance, and any engagement in behavioral therapy. Inattention/hyperactivity symptom questions and scoring is taken directly from the publicly available Vanderbilt Rating Scales, which is a commonly used, guideline-recommended tool for both diagnosis and management of ADHD for use by parents and teachers.

Intervention Type OTHER

Digital Education Handouts

The digital education handouts will be sent via email to the control group and will serve as an attention control. They will consist of information regarding a general pediatric health topic and will be emailed at intervals matching the RAMP requests in the intervention group.

Intervention Type OTHER

Other Intervention Names

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Remote ADHD Monitoring Program Standard of Care

Eligibility Criteria

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Inclusion Criteria

The child must

* be under the care of a participating provider
* be aged 5-11 at enrollment
* have a diagnosis of ADHD
* be initiating stimulant medication for treatment for the first time or have not received stimulant medication for the last 6 months
* be attending in-person elementary school

The Primary caregiver must

* be willing and legally able to give consent
* have access to a smartphone
* be English-speaking
* reside with the child at least 3 days per week
* complete an initial symptom assessment prior to starting stimulant treatment and be willing to provide a copy to the study team

The provider must

* manage ADHD care in patients age 5-11 years
* provide informed consent
* agree to use the RAMP platform if they care for patients randomized to use it
* agree to provide information to potential participants about the study and contact the research coordinator if interested

Exclusion Criteria

Child:

* has serious mental health comorbidities (Children with depression, anxiety, oppositional defiant disorder will be permitted to participate. Children with schizophrenia, bipolar disorder, conduct disorder and those who have been hospitalized for any mental health condition will be excluded from the study.)
* has severe neurodevelopment disorders (Children with well-controlled seizure disorders will be permitted to participate.)
* is currently receiving, or previously received, atypical antipsychotic medication treatment
* is or becomes pregnant
Minimum Eligible Age

5 Years

Maximum Eligible Age

11 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Medical University of South Carolina

OTHER

Sponsor Role collaborator

University of Mississippi Medical Center

OTHER

Sponsor Role collaborator

National Institutes of Health (NIH)

NIH

Sponsor Role collaborator

IDeA States Pediatric Clinical Trials Network

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University of Mississippi Medical Center

Jackson, Mississippi, United States

Site Status RECRUITING

Medical University of South Carolina

Charleston, South Carolina, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Song Ounpraseuth, PhD

Role: CONTACT

501-686-7233

Matthew Henry, MSc

Role: CONTACT

(501) 686-5547

Facility Contacts

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Hannah Ford, PhD

Role: primary

601-815-8413

Lacy Malloch, BS

Role: backup

601-815-4517

Claire MacGeorge, MD

Role: primary

843-876-8512

Shannon Cabaniss, BA

Role: backup

843-732-1839

Other Identifiers

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276280

Identifier Type: -

Identifier Source: org_study_id

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