Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women Using Inspiratory Muscle Strength Training
NCT ID: NCT06743269
Last Updated: 2025-04-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
30 participants
INTERVENTIONAL
2025-03-27
2027-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
SINGLE
Study Groups
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High-Resistance Inspiratory Muscle Strength Training Group
Subjects will partake in 5 sets of 6 inspiratory maneuvers (total: 30 maneuvers/session) 6 days a week for 6 weeks using the POWERbreathe K3 device to monitor adherence.
High-Resistance Inspiratory Muscle Strength Training
Performs inspiratory maneuvers at 55% maximal inspiratory pressure (PIMAX) during week 1, 65% PIMAX during week 2, and 75% PIMAX during weeks 3-6.
POWERbreathe K3 device
Inspiratory muscle training device
Low-Resistance Inspiratory Muscle Strength Training Group
Subjects will partake in 5 sets of 6 inspiratory maneuvers (total: 30 maneuvers/session) 6 days a week for 6 weeks using the POWERbreathe K3 device to monitor adherence.
Low-Resistance Inspiratory Muscle Strength Training
Performs inspiratory maneuvers at 15% maximal inspiratory pressure (PIMAX) for all 6 weeks.
POWERbreathe K3 device
Inspiratory muscle training device
Interventions
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High-Resistance Inspiratory Muscle Strength Training
Performs inspiratory maneuvers at 55% maximal inspiratory pressure (PIMAX) during week 1, 65% PIMAX during week 2, and 75% PIMAX during weeks 3-6.
Low-Resistance Inspiratory Muscle Strength Training
Performs inspiratory maneuvers at 15% maximal inspiratory pressure (PIMAX) for all 6 weeks.
POWERbreathe K3 device
Inspiratory muscle training device
Eligibility Criteria
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Inclusion Criteria
* Participants will be recruited from Rochester, MN and surrounding areas.
* Non-smokers.
* BMI \< 40kg/m\^2.
* No history of cardiovascular disease, except for hypertension.
Exclusion Criteria
* Participants will be screened for contraindications to inspiratory muscle strength training including, a history of spontaneous pneumothorax, collapsed lung that has not healed fully, a perforated eardrum that has not healed fully, and/or any other condition of the eardrum.
45 Years
60 Years
FEMALE
Yes
Sponsors
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Mayo Clinic
OTHER
Responsible Party
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Sarah E. Baker, Ph.D.
Principal Investigator
Principal Investigators
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Sarah Baker, PhD
Role: PRINCIPAL_INVESTIGATOR
Mayo Clinic
Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, United States
Countries
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Central Contacts
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Other Identifiers
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23-011042
Identifier Type: -
Identifier Source: org_study_id
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