Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
120 participants
INTERVENTIONAL
2025-07-21
2028-01-01
Brief Summary
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Detailed Description
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2. Explore the factors associated with seizure outcomes.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Open Surgery (anterior temporal lobectomy, ATL)
Open Surgery
Traditional Open Surgery
Minimally Invasive Surgery (MRgLITT)
Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT)
MRgLITT employs laser energy delivered through a stereotactically placed laser applicator to precisely ablate the epileptogenic tissue.
Interventions
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Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT)
MRgLITT employs laser energy delivered through a stereotactically placed laser applicator to precisely ablate the epileptogenic tissue.
Open Surgery
Traditional Open Surgery
Eligibility Criteria
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Inclusion Criteria
* Drug-resistant mesial temporal lobe epilepsy.
* Seizure frequency ≥ 1 time /month.
* Participants approved.
Exclusion Criteria
* Intracranial space occupying lesions.
* Individuals with significant medical comorbidities or conditions that pose an excessive risk for surgery, such as severe cardiovascular disease, respiratory disorders, or uncontrolled systemic infections.
ALL
No
Sponsors
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Beijing Tiantan Hospital
OTHER
Responsible Party
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Kai Zhang
Dr.
Locations
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Beijing Tiantan Hospital
Beijing, Beijing Municipality, China
Countries
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Central Contacts
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Facility Contacts
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References
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Mo J, Guo Z, Wang X, Zhang J, Hu W, Shao X, Sang L, Zheng Z, Zhang C, Zhang K. Magnetic resonance-guided laser interstitial thermal therapy vs. open surgery for drug-resistant mesial temporal lobe epilepsy: a propensity score matched retrospective cohort study. Int J Surg. 2024 Jan 1;110(1):306-314. doi: 10.1097/JS9.0000000000000811.
Other Identifiers
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KY2025-073-02
Identifier Type: -
Identifier Source: org_study_id
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