Comparative Effects of Sensory Re-education and Neural Mobilization in CTS Patients

NCT ID: NCT06686212

Last Updated: 2024-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-10

Study Completion Date

2025-07-30

Brief Summary

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The aim of study is to compare the effects of sensory re-education and neural mobilization in CTS patients.

Detailed Description

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This study will be randomized clinical trial that will be conducted at Services Hospital Lahore and Government Teaching Hospital Shahdara. In this study 48 participants with CTS will be included as per sample size calculation through non-probability convenience sampling technique. Participants that achieve the required standards of inclusion and exclusion criteria will be randomly allocated using online randomization tool into two groups. Group A will receive Sensory Re-education therapy, strengthening exercises and Kinesio taping for 60 minutes, Group B will be given neural mobilization techniques, strengthening exercises and Kinesio taping for 60 minutes with short rest intervals. Both treatments will be given 3 days per week for 12 weeks.

Conditions

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Carpal Tunnel Syndrome (CTS)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Group A: Sensory re-education program, strengthening exercises and kinesio taping

The patient will be given a session of 60 minutes 3 days in a week which includes : Splinting (15 minutes), Topical anesthesia spray (10 minutes ) and wrist massage (10 minutes).

* PNF using upper extremity (D2) pattern (5 minutes).
* Strengthening exercises (20 minutes) and Kinesio taping for 12 weeks.

Group Type EXPERIMENTAL

Sensory re-education+ strengthening exercises+ kinesio taping

Intervention Type OTHER

Sensory re-education. Splinting: as constant maintained touch with wrist holding in neutral position for 15 minutes.

Topical anesthesia spray on affected area for 10 minutes. Massage: apply massage over sensitive areas with same speed and pressure, then the light pressure with cotton, velvet, terry cloth, polyester and wool over sensitive area for 10 minutes.

PNF using upper extremity (D2) pattern including shoulder extension, adduction, internal rotation, wrist and fingers flexed and wrist ulnar deviated. 10-15 repetitions for 5 minutes.

Strengthening exercises: wrist flexion and extension, supination and pronation, opposition, gripping, ball squeeze and fingers pinching against resistance. 10-15 repetitions of each exercise for 20 minutes.

Kinesio taping: Taping will be applied twice a week for 12 weeks.

Group B:Neural mobilization of median nerve, strengthening exercises and kinesio taping.

The patient will be given a session of 60 minutes 3 days in a week which includes: ,Median nerve mobilization through various steps of gliding. (30 minutes).

* Free the bird exercise. (10 minutes).
* Strengthening exercises (20 minutes) and kinesio taping for 12 weeks.

Group Type EXPERIMENTAL

Neural mobilization+ Strengthening exercises+ Kinesio taping.

Intervention Type OTHER

The median nerve is mobilized through wrist flexion and extension with elbow straight and palm facing up.

Wrist flexion and extension with elbow flexed to 90 degrees with palm facing up 10-15 repetitions.

Wrist flexors stretch with extended arm and palm facing down 10-15 repetitions. Straight fist: hold your hand up with fingers straight. Full fist: bend your fingers to form a full fist. Median nerve stretch and wrist extension exercises for 30 minutes. Free the bird exercises, busy bee flexion shape of Z exercises and wall stretch exercise. (10-15 repetitions) for 10 minutes.

Strengthening exercises: wrist flexion and extension, supination and pronation, opposition, gripping, ball squeeze and fingers pinching against resistance. 10-15 repetitions each for 20 minutes.

Kinesio taping: The taping will be applied twice a week for 12 weeks.

Interventions

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Sensory re-education+ strengthening exercises+ kinesio taping

Sensory re-education. Splinting: as constant maintained touch with wrist holding in neutral position for 15 minutes.

Topical anesthesia spray on affected area for 10 minutes. Massage: apply massage over sensitive areas with same speed and pressure, then the light pressure with cotton, velvet, terry cloth, polyester and wool over sensitive area for 10 minutes.

PNF using upper extremity (D2) pattern including shoulder extension, adduction, internal rotation, wrist and fingers flexed and wrist ulnar deviated. 10-15 repetitions for 5 minutes.

Strengthening exercises: wrist flexion and extension, supination and pronation, opposition, gripping, ball squeeze and fingers pinching against resistance. 10-15 repetitions of each exercise for 20 minutes.

Kinesio taping: Taping will be applied twice a week for 12 weeks.

Intervention Type OTHER

Neural mobilization+ Strengthening exercises+ Kinesio taping.

The median nerve is mobilized through wrist flexion and extension with elbow straight and palm facing up.

Wrist flexion and extension with elbow flexed to 90 degrees with palm facing up 10-15 repetitions.

Wrist flexors stretch with extended arm and palm facing down 10-15 repetitions. Straight fist: hold your hand up with fingers straight. Full fist: bend your fingers to form a full fist. Median nerve stretch and wrist extension exercises for 30 minutes. Free the bird exercises, busy bee flexion shape of Z exercises and wall stretch exercise. (10-15 repetitions) for 10 minutes.

Strengthening exercises: wrist flexion and extension, supination and pronation, opposition, gripping, ball squeeze and fingers pinching against resistance. 10-15 repetitions each for 20 minutes.

Kinesio taping: The taping will be applied twice a week for 12 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients of both genders age 20-50 years with mild and moderate carpal tunnel syndrome.
* Patients having positive score on CTS specific test (Phalen's test and Tinel's test).
* Patients with pain, paresthesia and hyperesthesia at the course of median nerve.
* Patients that are clinically diagnosed with carpal tunnel syndrome by physician. Patients having BMI \>25 (kg/m2).

Exclusion Criteria

* Patients with polyneuropathies.
* Patients with carpal tunnel syndrome due to any systemic illness (diabetes mellitus, thyroid diseases and R.A).

Patients having cervical radiculopathy.

Patients with history of wrist fracture.

Patients getting steroid injections and after CTS surgery.

Obese and pregnant female with carpal tunnel syndrome.

Patients with any cognitive or neurological problems are excluded from study.
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Riphah International University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Muhammad Kashif, Phd

Role: STUDY_CHAIR

Riphah International University Lahore Punjab, Pakistan

Central Contacts

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Muhammad Kashif, PhD-PT

Role: CONTACT

+92 333 3125303

Iqra Liaqat, DPT

Role: CONTACT

+92 348 4942418

References

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Sheereen FJ, Sarkar B, Sahay P, Shaphe MA, Alghadir AH, Iqbal A, Ali T, Ahmad F. Comparison of Two Manual Therapy Programs, including Tendon Gliding Exercises as a Common Adjunct, While Managing the Participants with Chronic Carpal Tunnel Syndrome. Pain Res Manag. 2022 Jun 8;2022:1975803. doi: 10.1155/2022/1975803. eCollection 2022.

Reference Type BACKGROUND
PMID: 35719196 (View on PubMed)

Jimenez-Del-Barrio S, Cadellans-Arroniz A, Ceballos-Laita L, Estebanez-de-Miguel E, Lopez-de-Celis C, Bueno-Gracia E, Perez-Bellmunt A. The effectiveness of manual therapy on pain, physical function, and nerve conduction studies in carpal tunnel syndrome patients: a systematic review and meta-analysis. Int Orthop. 2022 Feb;46(2):301-312. doi: 10.1007/s00264-021-05272-2. Epub 2021 Dec 3.

Reference Type BACKGROUND
PMID: 34862562 (View on PubMed)

Hassan A, Beumer A, Kuijer PPFM, van der Molen HF. Work-relatedness of carpal tunnel syndrome: Systematic review including meta-analysis and GRADE. Health Sci Rep. 2022 Nov 2;5(6):e888. doi: 10.1002/hsr2.888. eCollection 2022 Nov.

Reference Type BACKGROUND
PMID: 36340637 (View on PubMed)

Abdolrazaghi HA, Khansari M, Mirshahi M, Ahmadi Pishkuhi M. Effectiveness of Tendon and Nerve Gliding Exercises in the Treatment of Patients With Mild Idiopathic Carpal Tunnel Syndrome: A Randomized Controlled Trial. Hand (N Y). 2023 Mar;18(2):222-229. doi: 10.1177/15589447211006857. Epub 2021 Apr 15.

Reference Type BACKGROUND
PMID: 33855879 (View on PubMed)

Lam NW, Goh HT, Kamaruzzaman SB, Chin AV, Poi PJ, Tan MP. Normative data for hand grip strength and key pinch strength, stratified by age and gender for a multiethnic Asian population. Singapore Med J. 2016 Oct;57(10):578-584. doi: 10.11622/smedj.2015164. Epub 2015 Nov 13.

Reference Type BACKGROUND
PMID: 26768064 (View on PubMed)

Almasi-Doghaee M, Boostani R, Saeedi M, Ebrahimzadeh S, Moghadam-Ahmadi A, Saeedi-Borujeni MJ. Carpal compression, Phalen's and Tinel's test: Which one is more suitable for carpal tunnel syndrome? Iran J Neurol. 2016 Jul 6;15(3):173-4. No abstract available.

Reference Type BACKGROUND
PMID: 27648179 (View on PubMed)

Du J, Yuan Q, Wang XY, Qian JH, An J, Dai Q, Yan XY, Xu B, Luo J, Wang HZ. Manual Therapy and Related Interventions for Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis. J Integr Complement Med. 2022 Dec;28(12):919-926. doi: 10.1089/jicm.2022.0542. Epub 2022 Jul 27.

Reference Type BACKGROUND
PMID: 35895497 (View on PubMed)

Ijaz MJ, Karimi H, Ahmad A, Gillani SA, Anwar N, Chaudhary MA. Comparative Efficacy of Routine Physical Therapy with and without Neuromobilization in the Treatment of Patients with Mild to Moderate Carpal Tunnel Syndrome. Biomed Res Int. 2022 Jun 22;2022:2155765. doi: 10.1155/2022/2155765. eCollection 2022.

Reference Type BACKGROUND
PMID: 35782066 (View on PubMed)

Other Identifiers

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REC/RCR&AHS/24/0233

Identifier Type: -

Identifier Source: org_study_id

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