Investigation of the Relation Between Trigger Digit and Carpal Tunnel Syndrome

NCT ID: NCT04072692

Last Updated: 2019-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

59 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-26

Study Completion Date

2019-06-13

Brief Summary

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The purpose of this study is to comprehend the association between the trigger digit and carpal tunnel syndrome based on the quantification of the tendon and nerve characteristics. It includes three parts.

The first part is an observational study. The aim of the first part is to attempts to measure the gliding and morphological characteristics of the flexor tendons and median nerve in the longitudinal or cross-sectional directions via the ultrasonographical images incorporating with the motion capture experiment of the wrist and fingers. The gliding and morphological features of the tendons and nerve will be compared under different postures or movement patterns of the wrist and hand.

The second part is an interventional study. The aim of the first part is to establishes a novel hybrid rehabilitation protocol which combines the tendon gliding exercise with nerve mobilization to treat either the trigger digit or the carpal tunnel syndrome. A randomized controlled trial to investigate the short-term treatment effect and the follow-up examination will be carried out as well.

The third part is an observational study. The aim of the first part is to investigate the effects of carpal tunnel release on the hand performances from functional perspectives. In addition, a novel wrist orthosis will be developed to eliminate the bowstringing effect of the flexor tendons after carpal tunnel release.

Detailed Description

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Conditions

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The Comorbidity Between the Trigger Digit and Carpal Tunnel Syndrome

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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1st part: The gliding properties of the tendons

No intervention. Subjects are measured by ultrasound under 5 different postures of the hand for forty minutes.

Group Type NO_INTERVENTION

No interventions assigned to this group

1st part: The gliding properties of the median nerve

No intervention. Subjects are measured by ultrasound under under 6 different postures of the wrist and hand and 5 different movement patterns of the wrist and hand for forty minutes.

Group Type NO_INTERVENTION

No interventions assigned to this group

2nd part: New hybrid rehabilitation strategy

The program includes pre-test, 8 times training, post-test and follow-up test.

For pre-test, subjects perform the specific hand movement under different exerting force conditions and 4 different angles of phalangeal joints and be asked to do Phalen test, Grip strength test, Pinch test and SWMT test. It takes 40 minutes.

For post-test, the same procedure is repeated again after completing all training.

For follow-up, the same procedure is repeated again 6 months after completing all training.

After pre-test, 8 times hybrid rehabilitation training are asked. There are two times in a week, and all training will be completed in one month. Each time will take forty minutes.

Group Type EXPERIMENTAL

Hybrid rehabilitation training

Intervention Type OTHER

Hybrid rehabilitation training is modified tendon gliding exercise with median nerve mobilization.

2nd part: Traditional strategy

The program includes pre-test, 8 times training, post-test and follow-up test.

For pre-test, subjects perform the specific hand movement under different exerting force conditions and 4 different angles of phalangeal joints and be asked to do Phalen test, Grip strength test, Pinch test and SWMT test. It takes 40 minutes.

For post-test, the same procedure is repeated again after completing all training.

For follow-up, the same procedure is repeated again 6 months after completing all training.

After pre-test, 8 times traditional rehabilitation training are asked. There are two times in a week, and all training will be completed in one month. Each time will take forty minutes.

Group Type EXPERIMENTAL

Traditional rehabilitation training

Intervention Type OTHER

Traditional rehabilitation training uses traditional physiotherapy, such as splint, therapeutic ultrasound and electrotherapy.

3rd part: The effect of carpal tunnel release

No intervention. The program includes pre-test, post-test and two times follow-up tests.

For pre-test, subjects perform the mechanical properties of the flexor tendon assessment and functional assessment of both hands before carpal tunnel release surgery. It takes 40 minutes.

For post-test, subjects perform the functional assessment of both hands one week after carpal tunnel release surgery. It takes 20 minutes.

For first follow-up, subjects perform the mechanical properties of the flexor tendon assessment and functional assessment of both hands one month after carpal tunnel release surgery. It takes 40 minutes.

For second follow-up, subjects perform the mechanical properties of the flexor tendon assessment and functional assessment of both hands two month after carpal tunnel release surgery. It takes 40 minutes.

Group Type NO_INTERVENTION

No interventions assigned to this group

3rd part: Wearable anti-bowstringing orthosis (WABO)

The program includes pre-test, post-test and two times follow-up tests.

For pre-test, subjects perform the mechanical properties of the flexor tendon assessment and functional assessment of both hands before carpal tunnel release surgery. It takes 40 minutes.

Subjects wear WABO in the morning and a splint at night within a week after carpal tunnel release surgery.

For post-test, subjects perform the functional assessment of both hands with and without wearing WABO and a splint one week after carpal tunnel release surgery. It takes 40 minutes.

From the third weeks after carpal tunnel release surgery, subjects wear WABO only in the morning.

For first follow-up, the same procedure in pre-test is repeated again one month after carpal tunnel release surgery. It takes 40 minutes.

For second follow-up, the same procedure in pre-test is repeated again two month after carpal tunnel release surgery.

Group Type EXPERIMENTAL

Wearable anti-bowstringing orthosis (WABO)

Intervention Type OTHER

WABO is a custom-designed orthosis to restrict the bowstringing effect of the flexor tendon in the carpal tunnel.

Interventions

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Hybrid rehabilitation training

Hybrid rehabilitation training is modified tendon gliding exercise with median nerve mobilization.

Intervention Type OTHER

Traditional rehabilitation training

Traditional rehabilitation training uses traditional physiotherapy, such as splint, therapeutic ultrasound and electrotherapy.

Intervention Type OTHER

Wearable anti-bowstringing orthosis (WABO)

WABO is a custom-designed orthosis to restrict the bowstringing effect of the flexor tendon in the carpal tunnel.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Healthy subjects without any history musculoskeletal diseases
2. Patients with carpal tunnel release surgery

Exclusion Criteria

* Subjects with fracture or surgery in the upper extremity.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Cheng-Kung University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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National Cheng-Kung University

Tainan City, , Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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A-ER-103-404

Identifier Type: -

Identifier Source: org_study_id

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