Utilizing of Physiological Parameters Predict the Prognosis of Cirrhotic Patients With Gastrointestinal Bleeding

NCT ID: NCT06680583

Last Updated: 2025-09-08

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 150 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-11-01
• Study Completion Date: 2025-12-31

Brief Summary

Can physiological indicators such as quick Sequential Organ Failure Assessment , Shock Index, and its derived indicators such as Modified Shock Index , Age Shock Index and Respiratory Adjusted Shock Index accurately predict the prognosis of cirrhosis patients with gastrointestinal bleeding? To explore the improvement of emergency and critical care patient management.

Detailed Description

Cirrhosis is a common chronic liver disease with gastrointestinal bleeding being one of its complications. Gastrointestinal bleeding is quite common in patients with cirrhosis, but its prognosis is difficult to accurately predict. In current clinical practice, critical care physicians often use physiological indicators to assess the risk level of patients. Among them, the Shock Index and its derived indicators such as the Modified Shock Index, Age Shock Index, and Respiratory Adjusted Shock Index have been widely used in other fields, but their actual value in patients with cirrhosis complicated by gastrointestinal bleeding is not yet clear.

The prognosis of cirrhosis patients with gastrointestinal bleeding affects the quality of life and survival of the patients, thus necessitating the establishment of a reliable prognostic assessment tool to assist critical care physicians in making rapid treatment decisions. The motivation of this study is to explore the application value of Shock Index-related indicators in predicting the prognosis of cirrhosis patients with gastrointestinal bleeding, in order to improve the medical efficiency for this specific group of critically ill patients.

Conditions

Liver Cirrhosis; Gastrointestinal Bleeding

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

cirrhosis

cirrhosis with gastrointestinal bleeding

physical indicators such as shock index relatives

Intervention Type: OTHER

shock index relatives indicators used in the prediction of cirrhosis with gastrointestinal bleeding

Interventions

physical indicators such as shock index relatives

shock index relatives indicators used in the prediction of cirrhosis with gastrointestinal bleeding

Intervention Type: OTHER

Other Intervention Names

MSI, Age SI, RASI

Eligibility Criteria

Exclusion Criteria

-

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

St. Martin De Porress Hospital

OTHER

Sponsor Role: lead

Responsible Party

Chia-hsi Chen

Emergency and Critical Care Physician

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Yeong-Chin Jou Jou, professor

Role: STUDY_DIRECTOR

St. Martin De Porres Hospital Education and Research

Locations

St. Martin De Porres Hospital

Tainan City, , Taiwan

Site Status: RECRUITING

Countries

Taiwan

Central Contacts

Chia-Hsi Chen, Physician

Role: CONTACT

urologist3509@gmail.com

886-5-2756000 ext. 3708

Chung-Jing Wang, professor

Role: CONTACT

medicine@stm.org.tw

886-5-2756000 ext. 3708

Facility Contacts

Koa, Miss

Role: primary

medicine@stm.org

886-5-2756000 ext. 3708

Loa, Miss

Role: backup

medicine@stm.org

886-5-2756000 ext. 3706

Study Documents

Document Type: Individual Participant Data Set

Physical indicators with shock index relatives are used in the prediction of prognosis on cirrhosis with gastrointestinal bleeding

View Document

Other Identifiers

physical parameters

Identifier Type: REGISTRY

Identifier Source: secondary_id

St. Martin De Porres Hospital

Identifier Type: -

Identifier Source: org_study_id