Validation of a Questionnaire to Measure Cough Severity

NCT ID: NCT06669897

Last Updated: 2025-09-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-01

Study Completion Date

2026-04-30

Brief Summary

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To design and validate a questionnaire that allows objective assessment of the severity of chronic cough

Detailed Description

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Chronic cough is a common disease that has important consequences for patients, ranging from physical to psychological and social aspects. However, there is currently no tool to objectively validate cough severity.

The aim of the study is to design and validate a questionnaire to objectively assess the severity of chronic cough.

Conditions

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Cough

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Questionnaire

Chronic cough

Questionnaire

Intervention Type OTHER

Chronic cough questionnaire

Interventions

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Questionnaire

Chronic cough questionnaire

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Aged between 30 and 99 years
* Clinical diagnosis of chronic cough or healthy volunteers
* Good understanding of Spanish

Exclusion Criteria

* Non-Spanish-speaking patients
* Inability to complete the questionnaires
* Failure to sign the informed consent form
Minimum Eligible Age

30 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Astrid Crespo-Lessmann, PhD

Role: PRINCIPAL_INVESTIGATOR

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Locations

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Hospital Universitario Hermanos Trias y Pujol

Badalona, Barcelona, Spain

Site Status ENROLLING_BY_INVITATION

Hospital Univesitario de Bellvitge

L'Hospitalet de Llobregat, Barcelona, Spain

Site Status RECRUITING

Parc Taulí Hospital Universitari

Sabadell, Barcelona, Spain

Site Status RECRUITING

Hospital del Mar

Barcelona, , Spain

Site Status RECRUITING

Hospital Clínic de Barcelona

Barcelona, , Spain

Site Status RECRUITING

Hospital de la Santa Creu i Sant Pau. Carrer Mas Casanovas 90.

Barcelona, , Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Astrid Crespo-Lessmann, PhD

Role: CONTACT

+34 93 556 56 01

Astrid Crespo, PhD

Role: CONTACT

+34 93 556 56 01

Facility Contacts

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Mariana Muñoz, MD

Role: primary

Ana Sogo, MD

Role: primary

Maria Pilar Ausin Herrero, MD

Role: primary

Ebymar Arismendi, MD

Role: primary

Astrid Crespo, MD

Role: primary

+34-935565972

References

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French CT, Irwin RS, Fletcher KE, Adams TM. Evaluation of a cough-specific quality-of-life questionnaire. Chest. 2002 Apr;121(4):1123-31. doi: 10.1378/chest.121.4.1123.

Reference Type BACKGROUND
PMID: 11948042 (View on PubMed)

McGarvey L, Gibson PG. What Is Chronic Cough? Terminology. J Allergy Clin Immunol Pract. 2019 Jul-Aug;7(6):1711-1714. doi: 10.1016/j.jaip.2019.04.012. Epub 2019 Apr 17.

Reference Type BACKGROUND
PMID: 31002958 (View on PubMed)

Morice AH, McGarvey LP, Dicpinigaitis PV. Cough hypersensitivity syndrome is an important clinical concept: a pro/con debate. Lung. 2012 Feb;190(1):3-9. doi: 10.1007/s00408-011-9351-y. Epub 2011 Dec 22.

Reference Type BACKGROUND
PMID: 22186805 (View on PubMed)

Haque RA, Usmani OS, Barnes PJ. Chronic idiopathic cough: a discrete clinical entity? Chest. 2005 May;127(5):1710-3. doi: 10.1378/chest.127.5.1710.

Reference Type BACKGROUND
PMID: 15888850 (View on PubMed)

Song WJ, Chang YS, Faruqi S, Kim JY, Kang MG, Kim S, Jo EJ, Kim MH, Plevkova J, Park HW, Cho SH, Morice AH. The global epidemiology of chronic cough in adults: a systematic review and meta-analysis. Eur Respir J. 2015 May;45(5):1479-81. doi: 10.1183/09031936.00218714. Epub 2015 Feb 5. No abstract available.

Reference Type BACKGROUND
PMID: 25657027 (View on PubMed)

Morice A. Chronic cough: epidemiology. Chron Respir Dis. 2008;5(1):43-7. doi: 10.1177/1479972307084252.

Reference Type BACKGROUND
PMID: 18303101 (View on PubMed)

Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE, Brown KK, Canning BJ, Chang AB, Dicpinigaitis PV, Eccles R, Glomb WB, Goldstein LB, Graham LM, Hargreave FE, Kvale PA, Lewis SZ, McCool FD, McCrory DC, Prakash UBS, Pratter MR, Rosen MJ, Schulman E, Shannon JJ, Hammond CS, Tarlo SM. Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006 Jan;129(1 Suppl):1S-23S. doi: 10.1378/chest.129.1_suppl.1S. No abstract available.

Reference Type BACKGROUND
PMID: 16428686 (View on PubMed)

Other Identifiers

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IIBSP-TOS-2023-133

Identifier Type: -

Identifier Source: org_study_id

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