Mindfulness-based Stress Reduction in Obese Women With Polycystic Ovary Syndrome (PICOS)

NCT ID: NCT06665789

Last Updated: 2025-05-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-31

Study Completion Date

2025-04-30

Brief Summary

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The aim of this study was to evaluate the effects of a mindfulness-based stress reduction (MBSR) program on Stress, depression, anxiety, cognitive triad and emotional appetite in obese women with polycystic ovary syndrome (PCOS).

Detailed Description

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The aim of this study was to evaluate the effects of mindfulness-based stress reduction (MBSR) program on stress, depression, anxiety, cognitive triad and emotional appetite in obese women with polycystic ovary syndrome (PCOS).

This study was designed as a single-blind pilot randomized controlled trial. It is planned to be conducted between November 2024 and January 2025 at Zeynep Kamil Women and Children's Diseases Education and Research Hospital.

Power analysis using G\*Power 3.0.10 showed that at least 44 samples were sufficient for 2 groups with Effect size 1. 72, 95% Power and 5% margin of error. Participants to be included in the groups were selected from the sample using a random sampling method with an equal distribution ratio (distribution ratio = 1:1).

Eligible women were randomized into the intervention group (n=22) and the control group (control) (n=22). Women assigned to the intervention group received the MBSR program. MBSR had eight weekly sessions of two hours each and a full-day retreat between the 7th and 8th sessions. The control group received routine care in the hospital but did not receive any other intervention during this period.

The pre-test data of the study were collected by the researcher using a face-to-face interview, a Personal Information Form containing demographic questions, and the measurement tools used in the study. At the end of the 8 weeks, the post-test data were collected using the same method.

The participants were given explanations about the MBSR program and it was stated how, for how long, and where to practice. The online MBSR program was completed by the participants in a way specific to each session (with mind, body, and breathing exercises). The MBSR program was implemented in this way for 8 weeks (eight sessions in total and one session per week). In addition, the participants were given homework (audio recording) to do throughout the week (until the next session) in the form of repeating mindfulness meditation practices. At the end of the eighth week, the measurement tools were re-administered to the participants who attended all eight sessions and completed their homework, and the post-test data were obtained.

Conditions

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Obesity Polycystic Ovary Syndrome Stress

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors
Single (Participant)

Study Groups

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Experimental

Mindfulness-based stress reduction training will be given to women selected for the experimental group for 8 weeks.

Group Type EXPERIMENTAL

Mindfulness-based Stress Reduction

Intervention Type BEHAVIORAL

An 8-week Mindfulness-based stress reduction training programme

Control

Women in the control group receive routine care at the same hospital's polyclinics.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Mindfulness-based Stress Reduction

An 8-week Mindfulness-based stress reduction training programme

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Women between the ages of 18-40
* Body mass index (BMI) ≥ 40 kg/m2
* Women with a diagnosis of polycystic ovary syndrome

Exclusion Criteria

* Psychiatric illness
* Pregnant women
* Thyroid dysfunction
* Cushing's syndrome
* Hyperprolactinemia
* Cancer history
* Pharmacological treatment for obesity
* Any type of bariatric surgery
* Absence of any psychiatric illness or comorbidities
* Current enrollment in a stress reduction program
* Mindfulness practice within the past 6 months (regular formal practice at least once a week)
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Saglik Bilimleri Universitesi

OTHER

Sponsor Role lead

Responsible Party

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Leyla Kaya

Assoc. Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Leyla Kaya, PhD

Role: PRINCIPAL_INVESTIGATOR

Saglik Bilimleri Universitesi

Locations

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Zeynep Kamil Women and Children's Diseases Training and Research Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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17.04.2024/34

Identifier Type: -

Identifier Source: org_study_id

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