The Effect of LDL557 on Improving Degenerative Arthritis in the Elderly

NCT ID: NCT06658821

Last Updated: 2025-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-27

Study Completion Date

2026-06-30

Brief Summary

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This project is to conduct a clinical trial of SYNBIO TECH INC.'s LDL557 capsule for joint protection. To understand the improvement of joint discomfort and inflammation after supplementation, we hope to provide an updated choice for modern people's joint protection.

Detailed Description

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Conditions

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Arthritis Joint Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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LDL557-HK capsule

Subjects will take one capsule of the experimental group(LDL557-HK capsule) within 30 minutes before lunch during the experimental period.

Group Type EXPERIMENTAL

LDL557-HK capsule

Intervention Type DIETARY_SUPPLEMENT

Subjects will take once a day during the experimental period. one LDL557-HK capsule(Heat-killed Lactobacillus delbrueckii subsp. lactis LDL557 1x10\^10cell) within 30 minutes before lunch.

Placebo capsule

Subjects will take one placebo capsule within 30 minutes before lunch during the experimental period.

Group Type PLACEBO_COMPARATOR

Placebo Capsule

Intervention Type DIETARY_SUPPLEMENT

Subjects will take once a day during the experimental period. one placebo capsule within 30 minutes before lunch.

Interventions

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LDL557-HK capsule

Subjects will take once a day during the experimental period. one LDL557-HK capsule(Heat-killed Lactobacillus delbrueckii subsp. lactis LDL557 1x10\^10cell) within 30 minutes before lunch.

Intervention Type DIETARY_SUPPLEMENT

Placebo Capsule

Subjects will take once a day during the experimental period. one placebo capsule within 30 minutes before lunch.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* BMI 18-40 kg/m2;
* Those with early stage degenerative arthritis symptoms judged by X-ray to be Kellgren-Lawrence Grading Scale level 1 or 2, and the physician determines that long-term treatment is not needed or WOMAC score\>2.0 or WOMAC total scale score\>12 or VAS score ≦6.

Exclusion Criteria

* Smoking
* alcoholism
* diabetes
* breastfeeding women and pregnant women.
* Those consuming dietary supplements were excluded.
* Those who use non-steroidal anti-inflammatory analgesics and those who have had joint surgery.
* Rheumatoid arthritis.
* Those who have had joint injections within 6 months.
* Those with cardiovascular and cerebrovascular, rheumatoid or mental diseases.
* Patients undergoing cancer treatment.
Minimum Eligible Age

45 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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SYNBIO TECH INC. Kaohsiung Taiwan

UNKNOWN

Sponsor Role collaborator

Chung Shan Medical University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Chung Shan Medical University

Taichung, , Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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CS2-24147

Identifier Type: -

Identifier Source: org_study_id

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