The Impact of Inflammatory Adhesion on the Prognosis of Colon Cancer Patients

NCT ID: NCT06655285

Last Updated: 2024-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

229 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-10-24

Study Completion Date

2024-10-27

Brief Summary

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The purpose of this study is to explore the impact of tumor-associated inflammatory adhesion on the prognosis of colon cancer patients.

Detailed Description

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In some colon cancer patients, although adhesions between the tumor tissue and surrounding organs are found during surgery, postoperative pathology confirms that the tumor has not directly invaded the adhered organs; instead, the adhesions are caused by tumor-associated inflammation. This condition is defined as tumor-associated inflammatory adhesion.

Currently, the impact of tumor-associated inflammatory adhesion on patient prognosis is still unclear. This study aims to explore the impact of tumor-associated inflammatory adhesion on the prognosis of colon cancer patients through the Surveillance, Epidemiology, and End Results (SEER) and Chinese multi-center databases.

Conditions

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Colon Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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the U.S. National Cancer Center SEER database

SEER\*Stat software (version 8.4.3) collected 17 registries cohort data on colon cancer patients between 2010 and 2019.

This was a retrospective study and no patient intervention was performed.

Intervention Type OTHER

This was a retrospective study and no patient intervention was performed.

Chinese multi-center database

Chinese multi-center database includes patients from January 2010 to December 2021 at 3 institutions.

This was a retrospective study and no patient intervention was performed.

Intervention Type OTHER

This was a retrospective study and no patient intervention was performed.

Interventions

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This was a retrospective study and no patient intervention was performed.

This was a retrospective study and no patient intervention was performed.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. The patient was pathologically diagnosed as colon adenocarcinoma by endoscopic biopsy before operation.
2. All patients were considered to have tumors invading adjacent organs during surgery
3. All patients underwent radical surgery.

Exclusion Criteria

1\. Patients with distant metastasis, recurrent colon cancer and pT4b CRC were excluded.
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cancer Institute and Hospital, Chinese Academy of Medical Sciences

OTHER

Sponsor Role lead

Responsible Party

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Jianqiang Tang

Associate professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cancer Hospital Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Other Identifiers

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NCC3650

Identifier Type: -

Identifier Source: org_study_id

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