Assessment of I-PRF Versus Nano MTA Combined with I-PRF Scaffold in Vital Pulp Therapy in Mature Mandibular First Molars

NCT ID: NCT06640205

Last Updated: 2024-10-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-03

Study Completion Date

2025-09-02

Brief Summary

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Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF in pulpotomy in mature Mandibular First Molars

Detailed Description

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Clinical and Radiographic Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF Scaffold in Vital Pulp Therapy in Mandibular First Molars with Closed Apices: "Randomized Controlled Trial"

Conditions

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Pulpotomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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MTA Pulpotomy

using MTA as pulpotomy capping agent in mature permanent teeth

Group Type ACTIVE_COMPARATOR

pulpotomy

Intervention Type PROCEDURE

Removal of coronal pulp tissue and then placing pulpotomy agent

I-PRF pulpotomy

using I-PRF as pulpotomy capping agent in mature permanent teeth

Group Type EXPERIMENTAL

pulpotomy

Intervention Type PROCEDURE

Removal of coronal pulp tissue and then placing pulpotomy agent

I-PRF combined with Nano MTA pulpotomy

using nano MTA mixed with I-prf as pulpotomy capping agent in mature permanent teeth

Group Type EXPERIMENTAL

pulpotomy

Intervention Type PROCEDURE

Removal of coronal pulp tissue and then placing pulpotomy agent

Interventions

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pulpotomy

Removal of coronal pulp tissue and then placing pulpotomy agent

Intervention Type PROCEDURE

Other Intervention Names

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full pulpotomy vital pulp therapy

Eligibility Criteria

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Inclusion Criteria

* Patients suffering from Symptomatic irreversible pulpitis in mature mandibular molars only will be involved.

* Patients of either gender aged from 15-30.
* Tooth should give positive response to cold test.
* The tooth is restorable
* Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
* Patients who will agree to the consent and will commit to follow-up period.
* Patients with mature root.
* Patients with no internal or external resorption and no periapical lesions.
* Soft tissues around the tooth are normal with no swelling or sinus tract.

Exclusion Criteria

* Patients with immature roots.

* Haemostasias after 10 minutes can not be controlled after total pulpotomy
* Patients with periapical lesions or infections.
* Pregnant females.
* Patients with fistula or swelling
* Patients with necrotic pulp.
Minimum Eligible Age

15 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Future University in Egypt

OTHER

Sponsor Role lead

Responsible Party

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Abdelrahman Mohamed Elsayed Metwally Omar

Principle investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Abdelrahman Mo Omar, Master

Role: STUDY_CHAIR

Future University in Egypt

Locations

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Future university in egypt

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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abdelrahman Mo Omar, Master

Role: CONTACT

00201000424892 ext. 002

Mai Sh abdelwahed, Master

Role: CONTACT

01068609957 ext. 002

Facility Contacts

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Abdelrahman Mo omar, Master

Role: primary

01000424892 ext. 002

Other Identifiers

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(32)/8-2023

Identifier Type: -

Identifier Source: org_study_id

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