Phantom Limb Pain in Amputees After the 2023 Türkiye Earthquake

NCT ID: NCT06617728

Last Updated: 2024-10-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

39 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-06

Study Completion Date

2024-05-30

Brief Summary

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The goal of this observational study is to investigate the prevalence and persistence of phantom limb pain (PLP) among amputees who experienced limb loss due to injuries sustained during the 2023 Türkiye earthquake. The main questions it aims to answer are:

What is the prevalence of phantom limb pain among earthquake-related amputees at different follow-up intervals? How do different pain management strategies, such as regional analgesia versus intravenous analgesia, affect the severity and persistence of phantom limb pain? Researchers will compare participants receiving regional analgesia to those receiving intravenous analgesia to see if regional techniques are associated with lower rates of phantom limb pain and improved quality of life.

Participants will:

Complete pain assessments using standardized questionnaires at 1 week, 3 months, 6 months, and 12 months post-amputation.

Provide information on their pain management experiences and the impact on their daily activities.

Detailed Description

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This observational study aims to assess the prevalence, characteristics, and management of phantom limb pain (PLP) among individuals who underwent amputations due to injuries sustained during the 2023 Türkiye earthquake. Conducted at the Mersin University Pain Clinic, the study involves 39 patients who were followed for 12 months post-amputation. The primary focus is to evaluate how different analgesic methods, such as regional versus intravenous analgesia, influence the development and persistence of PLP and associated phantom limb sensations (PLS).

Patients were recruited from those treated at Mersin University Hospital immediately following the earthquake. Inclusion criteria included individuals aged 5 years and older who experienced amputation due to earthquake-related trauma. Exclusion criteria included pre-existing psychiatric disorders, history of neuropathic pain in the amputated limb, or inability to communicate due to cognitive impairment.

The study's primary outcomes are the prevalence of PLP and PLS at 1 week, 3 months, 6 months, and 12 months post-amputation. Pain intensity is measured using the Visual Analog Scale (VAS), and the impact of different analgesic techniques on pain severity and quality of life is analyzed. Secondary outcomes include the incidence of residual limb pain and the effectiveness of various pain management strategies in reducing pain symptoms over time.

This study is expected to contribute valuable insights into the management of PLP in disaster-related amputees, providing evidence to guide clinical practice and improve patient outcomes in similar post-disaster settings.

Conditions

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Phantom Limb Pain Amputation Pain Management Earthquake

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1: Regional Analgesia Cohort

Participants receiving regional analgesia for pain management.

Intervention 1: Regional Analgesia

Intervention Type PROCEDURE

Regional analgesia techniques like epidural or peripheral nerve blocks.

Group 2: Intravenous (IV) Analgesia Cohort

Participants receiving IV analgesia for pain management.

Intervention 2: Intravenous (IV) Analgesia

Intervention Type DRUG

IV medications used for pain control, including opioids and non-opioid analgesics.

Interventions

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Intervention 1: Regional Analgesia

Regional analgesia techniques like epidural or peripheral nerve blocks.

Intervention Type PROCEDURE

Intervention 2: Intravenous (IV) Analgesia

IV medications used for pain control, including opioids and non-opioid analgesics.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Individuals aged 5 years and older.
* Patients who have undergone amputation due to injuries sustained during the 2023 Türkiye earthquake.
* Experiencing phantom limb pain (PLP) as confirmed by a structured questionnaire.
* Able to provide informed consent or have consent provided by a legal guardian if under the age of 18.

Exclusion Criteria

* Pre-existing psychiatric disorders that could interfere with pain perception or reporting.
* History of neuropathic pain in the amputated limb prior to the earthquake.
* Underwent surgical interventions in other parts of the body that may affect pain assessment.
* Inability to communicate effectively due to cognitive impairment or other medical conditions.
Minimum Eligible Age

5 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mesut Bakır

OTHER

Sponsor Role lead

Responsible Party

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Mesut Bakır

Clinical Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Mesut Bakır, Assoc. Prof

Role: STUDY_CHAIR

Mersin University Faculty of Medicine, Pain Clinic

Locations

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Mersin University Faculty of Medicine

Mersin, Yenişehir, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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TURK-PLP-2023

Identifier Type: -

Identifier Source: org_study_id

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