The Effect of Warming and Vibration Applications on Pain in Newborns

NCT ID: NCT06607575

Last Updated: 2025-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

140 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-15

Study Completion Date

2025-03-12

Brief Summary

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This study aimed to determine the effects of warming and vibration applications on pain during heel blood collection in newborns.

H1: Warming application has a positive effect on pain during heel blood collection in newborns.

H2: Vibration application has a positive effect on pain during heel blood collection in newborns.

H3: The combined application of warming and vibration during heel blood collection in newborns has a positive effect on pain.

Detailed Description

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Heel blood collection is frequently used for neonatal metabolic screening and analysis of bilirubin, glucose and other biochemical/hematologic parameters. This process is both painful and stressful for the newborn. Pain experience in the neonatal period can cause intense stress in the infant and cause physiopathological changes such as respiratory irregularity, impaired thermoregulation, changes in heart rhythm, changes in oxygen saturation and blood pressure. Therefore, it is recommended to use evidence-based non-pharmacological methods to reduce the pain experiences of newborns and to minimize the short and long-term negative effects of pain.

Based on this rationale, this study was planned to evaluate the effect of non-pharmacologic methods on pain and procedure time together.

Conditions

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Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Control group

Newborns who will be subjected to routine practices during heel blood collection procedure and who will not be subjected to warming and vibration will constitute the control group.

Group Type OTHER

Control group

Intervention Type OTHER

1. The procedure for heel blood collection will be performed.
2. Pain assessment will be performed with the N-PASS scale during and after the procedure.

Experimental group (warming)

Newborns who will be subjected to warming application during the heel blood collection procedure will constitute the 1st experimental group.

Group Type EXPERIMENTAL

Warming

Intervention Type OTHER

1. The cotton sock will be warmed under the heater for 3 minutes. The sock will be put on the newborn and taken off after 3 minutes.
2. The procedure for heel blood collection will be performed.
3. Pain assessment will be performed with the N-PASS scale during and after the procedure.

Experimental group (vibration)

Newborns who will be subjected to vibration during the heel blood collection procedure will constitute the 2nd experimental group.

Group Type EXPERIMENTAL

Vibration

Intervention Type OTHER

1. A rechargeable toothbrush will be prepared for the newborn to whom vibration will be applied. The vibration process will be applied to the midline of the gastrocnemius muscle for 3 minutes.
2. The procedure for heel blood collection will be performed.
3. Pain assessment will be performed with the N-PASS scale during and after the procedure.

Experimental group (warming and vibration)

Newborns who will be subjected to both warming and vibration during the heel blood collection procedure will constitute the 3rd experimental group.

Group Type EXPERIMENTAL

Warming and vibration

Intervention Type OTHER

1. After the socks are warmed, they will be put on the newborn\'s feet and both warming and vibration will be applied for 3 minutes.
2. The procedure for heel blood collection will be performed.
3. Pain assessment will be performed with the N-PASS scale during and after the procedure.

Interventions

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Control group

1. The procedure for heel blood collection will be performed.
2. Pain assessment will be performed with the N-PASS scale during and after the procedure.

Intervention Type OTHER

Warming

1. The cotton sock will be warmed under the heater for 3 minutes. The sock will be put on the newborn and taken off after 3 minutes.
2. The procedure for heel blood collection will be performed.
3. Pain assessment will be performed with the N-PASS scale during and after the procedure.

Intervention Type OTHER

Vibration

1. A rechargeable toothbrush will be prepared for the newborn to whom vibration will be applied. The vibration process will be applied to the midline of the gastrocnemius muscle for 3 minutes.
2. The procedure for heel blood collection will be performed.
3. Pain assessment will be performed with the N-PASS scale during and after the procedure.

Intervention Type OTHER

Warming and vibration

1. After the socks are warmed, they will be put on the newborn\'s feet and both warming and vibration will be applied for 3 minutes.
2. The procedure for heel blood collection will be performed.
3. Pain assessment will be performed with the N-PASS scale during and after the procedure.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Newborns at 38 weeks of gestation and above
* Healthy newborns

Exclusion Criteria

* Newborns with any lower extremity anomalies
* Newborns with congenital diseases
Minimum Eligible Age

1 Day

Maximum Eligible Age

28 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Acibadem University

OTHER

Sponsor Role lead

Responsible Party

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Zehra Kan Onturk

Assoc. Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hande Keskin Nurse

Role: PRINCIPAL_INVESTIGATOR

Acibadem University

Locations

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Acıbadem University

Istanbul, Ata, Turkey (Türkiye)

Site Status

Acıbadem University

Istanbul, Ataşehir, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Avan Antepli N, Bilsin Kocamaz E, Gungormus Z. The Effect of Vibration on Pain During Heel Lance Procedures in Newborns: A Randomized Controlled Trial. Adv Neonatal Care. 2022 Apr 1;22(2):E43-E47. doi: 10.1097/ANC.0000000000000918.

Reference Type BACKGROUND
PMID: 34334677 (View on PubMed)

Shepherd AJ, Glenesk A, Niven CA, Mackenzie J. A Scottish study of heel-prick blood sampling in newborn babies. Midwifery. 2006 Jun;22(2):158-68. doi: 10.1016/j.midw.2005.07.002. Epub 2005 Dec 28.

Reference Type BACKGROUND
PMID: 16386341 (View on PubMed)

Ray R, Godwin Y, Shepherd A. Convective burn from use of hairdryer for heel warming prior to the heel prick test - a case report. BMC Pediatr. 2011 May 10;11:30. doi: 10.1186/1471-2431-11-30.

Reference Type BACKGROUND
PMID: 21569274 (View on PubMed)

Napiorkowska-Orkisz M, Gutysz-Wojnicka A, Tanajewska M, Sadowska-Krawczenko I. Evaluation of Methods to Minimize Pain in Newborns during Capillary Blood Sampling for Screening: A Randomized Clinical Trial. Int J Environ Res Public Health. 2022 Jan 13;19(2):870. doi: 10.3390/ijerph19020870.

Reference Type BACKGROUND
PMID: 35055694 (View on PubMed)

Hassan Z, Shah M. Scald injury from the Guthrie test: should the heel be warmed? Arch Dis Child Fetal Neonatal Ed. 2005 Nov;90(6):F533-4. doi: 10.1136/adc.2005.072678.

Reference Type BACKGROUND
PMID: 16244215 (View on PubMed)

Other Identifiers

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ATADEK 2023-10/403

Identifier Type: -

Identifier Source: org_study_id

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