Implants Placement with Simultaneous Soft Tissue Augmentation Using a Collagen Matrix Compared to Connective Tissue Graft: a Pilot Study

NCT ID: NCT06585813

Last Updated: 2024-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

4 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-10

Study Completion Date

2024-06-20

Brief Summary

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Background: To our knowledge, no study evaluated the use of VCMX at multiple implant sites and compared its efficacy and safety to a SCTG with the same dimensions. Therefore, we propose in the present protocol to evaluate the efficacy of VMCX to increase the thickness and height of soft tissue when placed at the time of multiple implant placement, as compared to SCTG.

Material and Methods: This study will be conducted in the saint joseph university periodontology department on at least 5 to 10 patients. The studied sites are the edentulous posterior mandible in a split-mouth model. The test groups are the groups grafted with VCMX and the control groups are the groups grafted with SCTG.

Some studies have been reported to compare these two techniques. But the specificity of our study is soft tissue augmentation on multiple implant sites in a split-mouth design.

Detailed Description

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Conditions

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Soft Tissue Thickness Arround Implants

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Fibrogide group

we are comparing the grafting of fibrogide(VCMX) with the connective tissue graft on multiple implant placement

Group Type EXPERIMENTAL

dental implant

Intervention Type PROCEDURE

we placed our implants and simultaneously grafted either fibroguide or CTG and after 3 months we did the second stage surgery

Fibrogide membrane

Intervention Type PROCEDURE

we were comparing the efficacy of Fibrogide with the Connective tissue graft

second stage

Intervention Type PROCEDURE

second stage to determine the thickness gained after the graft and to place a healing abutment

Connective Tissue graft Group

Group Type EXPERIMENTAL

dental implant

Intervention Type PROCEDURE

we placed our implants and simultaneously grafted either fibroguide or CTG and after 3 months we did the second stage surgery

connective tissue graft

Intervention Type PROCEDURE

the control group was the connective tissue graft group and the test group was the Fibrogide group

second stage

Intervention Type PROCEDURE

second stage to determine the thickness gained after the graft and to place a healing abutment

Interventions

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dental implant

we placed our implants and simultaneously grafted either fibroguide or CTG and after 3 months we did the second stage surgery

Intervention Type PROCEDURE

Fibrogide membrane

we were comparing the efficacy of Fibrogide with the Connective tissue graft

Intervention Type PROCEDURE

connective tissue graft

the control group was the connective tissue graft group and the test group was the Fibrogide group

Intervention Type PROCEDURE

second stage

second stage to determine the thickness gained after the graft and to place a healing abutment

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Adults ;18 years old.
* Patients with adequate oral hygiene (FMPI\<20% and FMBI\<20%).
* Healed implant sites (tooth extraction at least 8 to 12 weeks before enrolment).
* Patients who need prosthetic rehabilitation of at least two implants in the left and right posterior mandibular area.
* Inadequate amount of soft tissue where the implants are planned to be placed: thin mucosal tissues covering the edentulous alveolar ridge.
* Compliant patients are willing to sign an informed consent.

Exclusion Criteria

* Uncontrolled periodontal disease.
* Heavy smoker (\>10 cigarettes per day).
* General contraindications for dental surgical treatment.
* Insufficient bone volume for implant placement requiring bone augmentation procedures.
* History of malignancy, radiotherapy, or chemotherapy for malignancy within the past 5 years.
* Pregnancy or breastfeeding.
* Previous and concurrent medication affecting bone and mucosal healing.
* Disease affecting bone and connective tissue metabolism.
* Immediate implant placement.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Saint-Joseph University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nada Naaman, DDS,Msc in periodontology,PHD

Role: STUDY_DIRECTOR

Saint-Joseph University /American University of Baghdad

Locations

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Saint-Joseph University

Beirut, Beyrouth, Lebanon

Site Status

Countries

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Lebanon

Other Identifiers

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USJ -2023-62

Identifier Type: -

Identifier Source: org_study_id

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