Comparison Between Different Ways for Using Lidocaine During FB
NCT ID: NCT06563050
Last Updated: 2024-08-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
240 participants
INTERVENTIONAL
2024-09-30
2026-11-30
Brief Summary
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Detailed Description
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The reduction in cough not only improves patient comfort but also makes the procedure easier for the operator.
Among agents used for topical anesthesia, lidocaine is the most widely used drug because of its safety and favorable pharmacokinetic profile.
Lidocaine is available in various formulations (gel or solution) and can be delivered to the respiratory passages by using different modes (spray, nebulization, transtracheal injection, bronchoscope instillation, and others).
In this study, will compare the efficacy and safety of nebulized lidocaine, oropharyngeal lidocaine spray, or their combination for topical anesthesia in subjects undergoing diagnostic FB, for better outcome.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
In group B will underwent 10% lidocaine spray solution will be sprayed 10 times at the oropharynx at 5 s interval.
Group C: both nebulization and spray will be performed in the same manner except the number of spray will be 2 instead 10.
SUPPORTIVE_CARE
DOUBLE
Study Groups
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Nebulized lidocaine
Subjects in group A underwent nebulization with 5 mL of 2% lidocaine for 15 minutes by using a jet nebulizer.
Nebulized lidocaine
Subjects in group A underwent nebulization with 5 mL of 2% lidocaine for 15 minutes by using a jet nebulizer.
Lidocaine spray
In group B will underwent 10% lidocaine spray solution will be sprayed 10 times at the oropharynx at 5 s interval.
Lidocaine spray
Subjects in group B will underwent 10% lidocaine spray solution will be sprayed 10 times at the oropharynx at 5 s interval.
Combination( Nebulized lidocaine and lidocaine spray)
Group C: both nebulization and spray will be performed in the same manner except the number of spray will be 2 instead 10.
Combination of nebulized lidocaine and lidocaine spray
Group C: both nebulization and spray will be performed in the same manner except the number of spray will be 2 instead 10.
Interventions
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Nebulized lidocaine
Subjects in group A underwent nebulization with 5 mL of 2% lidocaine for 15 minutes by using a jet nebulizer.
Lidocaine spray
Subjects in group B will underwent 10% lidocaine spray solution will be sprayed 10 times at the oropharynx at 5 s interval.
Combination of nebulized lidocaine and lidocaine spray
Group C: both nebulization and spray will be performed in the same manner except the number of spray will be 2 instead 10.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Pregnancy.
* hemodynamic instability.
* failure to provide informed consent.
18 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Bassem Gadallah Gad-Elkariem Kalam
Resident doctor at Chest Diseases Department
Principal Investigators
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Mohamed Mostafa Abdelhadi
Role: STUDY_DIRECTOR
Professor of Chest Diseases and Tuberculosis
Montaser Gamal Ahmed
Role: STUDY_DIRECTOR
lecturer of Chest Diseases and Tuberculosis
Nermeen Mohammed Abuelkassem
Role: STUDY_DIRECTOR
lecturer of Chest Diseases and Tuberculosis
Central Contacts
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Other Identifiers
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Lidocaine use during FB
Identifier Type: -
Identifier Source: org_study_id
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