Tiotropium in Patients With Tuberculosis (TB) Destroyed Lung
NCT ID: NCT01365702
Last Updated: 2011-06-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
70 participants
OBSERVATIONAL
2011-06-30
2012-12-31
Brief Summary
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Detailed Description
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Previous large randomized controlled trials, targeting patients with smoking related moderate to severe COPD,demonstrated that tiotropium improved quality of life and respiratory symptom with tolerable long-term safety. The investigators want to evaluate whether tiotropium can improve chronic respiratory symptom,an lung function in patients with COPD due to TB destroyed lung.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Tiotropium in TB destroyed lung
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* never smoker or light smoker (\<10 pack-year)
* destruction of lung parenchyme, lung volume loss,secondary bronchiectasis due to tuberculosis in chest radiographs or chest CT, confirmed by board-certificate radiologist
* airflow obstruction confirmed by pulmonary function test, FEV1/FVC \<70%
Exclusion Criteria
* patients with active tuberculosis or current antituberculous medication
* patients under chemotherapy or other immunosuppressant therapy such as glucocorticoid.
* active infection such as pneumonia, tuberculosis
* patients who are illiterate
* patients with dementia
* pregnant or to be pregnant
* previous lung resection surgery history
18 Years
ALL
No
Sponsors
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Seoul National University Bundang Hospital
OTHER
Responsible Party
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Department of Internal Medicine, Seoul National University Bundang Hospital
Principal Investigators
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Sei Won Lee, M.D.
Role: PRINCIPAL_INVESTIGATOR
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute of Medical research center, Seoul National University Bundang Hospital
Locations
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Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Countries
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Facility Contacts
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Other Identifiers
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SNUBH_TLD and spiriva
Identifier Type: -
Identifier Source: org_study_id
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