Burn Coverage of Burn by Tilapia Fish Skin

NCT ID: NCT06549569

Last Updated: 2024-08-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-01

Study Completion Date

2024-08-01

Brief Summary

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The goal of this experimental study is to compare TFS and regular dressings as coverage for acute thermal burns. The main question it aims to answer is:

Is TFS effective in treating thermal burns? burn induction was done on rabbits to obtain second-degree thermal burn, followed by coverage with TFS

Detailed Description

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Nile Tilapia Fish Skin (NTFS) has been suggested as an option for biological material for the management of burns. Nile Tilapia Fish Skin also presented a large composition of type I collagen, morphology similar to human skin and high resistance and tensile extension at the break. We chose Baladi rabbits for their relatively ease of handling, accommodation and resistance to surgical aggressions and infectious processes, with low mortality. However, the choice of male rabbits is due to variations in hormonal cycles in females that could intervene in the process of tissue repair.

This experimental model was established to evaluate healing process and outcome results after application of Tilapia Fish Skin on acute contact thermal that was done in order to obtain injuries with the same size and depth.

Conditions

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Tilapia Fish Skin in Burn Coverage

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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TFS

thermal burn coverage with Tilapia fish skin

TFS

Intervention Type PROCEDURE

burn coverage with TFS

regular dressing

thermal burn coverage with regular dressing

TFS

Intervention Type PROCEDURE

burn coverage with TFS

Interventions

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TFS

burn coverage with TFS

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- healthy male one year old rabbit

Exclusion Criteria

* female unhealthy rabbits
Minimum Eligible Age

1 Year

Maximum Eligible Age

18 Months

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Aswan University

OTHER

Sponsor Role lead

Responsible Party

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Amira Anter

resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Amira Anter

Aswān, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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696/11/22

Identifier Type: -

Identifier Source: org_study_id

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