Topo-Pachymetric Customized Accelerated Epi-On Vs Accelerated Epi-Off Corneal Cross Linking in Keratoconus Management
NCT ID: NCT06549387
Last Updated: 2024-08-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
55 participants
INTERVENTIONAL
2024-08-15
2025-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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The topo-pachimetric customized accelerated epithelium-On (aCFXL group)
Corneal cross linking
Applying UVA irradiation to the cornea after soaking with riboflavin
The standard accelerated CXL (aCXL) protoco
Corneal cross linking
Applying UVA irradiation to the cornea after soaking with riboflavin
Progressive Fluence Epi-on accelerated crosslinking M nomogram
Corneal cross linking
Applying UVA irradiation to the cornea after soaking with riboflavin
Interventions
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Corneal cross linking
Applying UVA irradiation to the cornea after soaking with riboflavin
Eligibility Criteria
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Inclusion Criteria
2. Corrected distance visual acuity (CDVA) of ≥ 0.3 Snellen.
3. Central corneal thickness (de-epithelialized) of ≥ 400 micron.
4. Corneal endothelial count of ≥ 2000.
Exclusion Criteria
2. The presence of lesions other than keratoconus, central or paracentral scaring
3. History of Cross linking
4. History of viral keratitis
5. Connective tissue diseases
6. Pregnancy or lactation during the study.
7. The presence of nystagmus
18 Years
ALL
Yes
Sponsors
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Kasr El Aini Hospital
OTHER
Responsible Party
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Paula Sameh Youssef
M.Sc.
Locations
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Kasr Al Ainy
Cairo, , Egypt
Countries
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Facility Contacts
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Other Identifiers
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_MD-402-2023_
Identifier Type: -
Identifier Source: org_study_id
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