Acceptance and Commitment Therapy (ACT) in Groups for Obsessive Compulsive Disorder: A Clinical Trial in Brazil

NCT ID: NCT06548893

Last Updated: 2024-08-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-08-10

Study Completion Date

2026-06-20

Brief Summary

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The goal of this clinical trial is to learn if Acceptance and Commitment Therapy (ACT) + Exposure and Response Prevention (ERP) in Group is effective to Obsessive Compulsive Disorder (OCD) in adults.

Researchers will compare intervention to control group to see if those who attend the group therapy have better results than control group.

Participants will go through a 16-week group therapy based on a protocol designed by Michael Twohig (Twohig et al, 2018).

* Participants will not have any medication adjustment during therapy
* Participants will be assessed 3 times throughout the therapy, plus an assessment in a 6-month follow-up.

Detailed Description

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The goal of this clinical trial is to learn if Acceptance and Commitment Therapy (ACT) + Exposure and Response Prevention (ERP) in Group is effective to Obsessive Compulsive Disorder (OCD) in adults. The main questions it aims to answer are:

* Can ACT in groups help decrease the severity of OCD symptoms?
* Can ACT in groups help increase psychological flexibility in this group?
* Can ACT in groups help increase quality of life in this group?

Researchers will compare intervention (n=16) to control group (n=8) to see if those who attend the group therapy have better results than control group.

We will perform an unequal randomization in a 2:1 ratio, in blocks of 6, for allocation to each group. The assessor of the outcomes of interest will be blinded to the group to which the participant was assigned

Participants will go through a 16-week group therapy based on a protocol designed by Michael Twohig (Twohig et al, 2018).

* Participants will not have any medication adjustment during therapy
* Participants will be assessed 3 times throughout the therapy, plus an assessment in a 6-month follow-up.

Conditions

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Obsessive-Compulsive Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized controlled trial
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
Only the team member who will apply the questionnaires/scales will be masked.

Study Groups

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Group psychotherapy with ACT

16 sessions of group psychotherapy based on ACT + exposure with response prevention (EPR)

Group Type EXPERIMENTAL

Group acceptance and commitment therapy (ACT)

Intervention Type OTHER

Group psychotherapy based on ACT + EPR

Treatment as usual

Patients will follow their usual treatment, without adding ACT-based group psychotherapy

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Group acceptance and commitment therapy (ACT)

Group psychotherapy based on ACT + EPR

Intervention Type OTHER

Other Intervention Names

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Group Psychotherapy Acceptance and Commitment Therapy Psychotherapy

Eligibility Criteria

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Inclusion Criteria

* OCD diagnosis according to DMS-5/ Minimum score of 20 in YBOCS

Exclusion Criteria

* Psychotic disorder, maniac episode, intellectual disability, Chemical dependency, Suicidal risk, another current psychotherapy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universidade Federal do Paraná

OTHER

Sponsor Role lead

Responsible Party

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Luciana Midori Samezima

Ms

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gabriela M Ferreira, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Universidade Federal do Paraná

Locations

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Universidade Federal Do Paraná

Curitiba, Paraná, Brazil

Site Status

Countries

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Brazil

References

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Twohig MP, Abramowitz JS, Smith BM, Fabricant LE, Jacoby RJ, Morrison KL, Bluett EJ, Reuman L, Blakey SM, Ledermann T. Adding acceptance and commitment therapy to exposure and response prevention for obsessive-compulsive disorder: A randomized controlled trial. Behav Res Ther. 2018 Sep;108:1-9. doi: 10.1016/j.brat.2018.06.005. Epub 2018 Jun 22.

Reference Type BACKGROUND
PMID: 29966992 (View on PubMed)

Related Links

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https://www.utahact.com/treatment-protocols.html

ACT+ERP for OCD: This is a 16-session twice-weekly therapist manual for OCD describing ERP conducted from an ACT framework.

Other Identifiers

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61795622.3.0000.0096

Identifier Type: -

Identifier Source: org_study_id

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