iCBT for Adult Obsessive-Compulsive Disorder

NCT ID: NCT07081438

Last Updated: 2025-07-31

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 25 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-09-01
• Study Completion Date: 2027-03-01

Brief Summary

The goal of the study is to assess the feasibility, acceptability, and potential effects of therapist-guided internet-delivered cognitive-behavior therapy (iCBT) for adult obsessive-compulsive disorder, using a recently developed digital platform.

Detailed Description

Although cognitive-behavior therapy (CBT) is a well-established first-line treatment for many mental disorders, very few patients receive it due to the shortage of trained professionals, the costs of face-to-face therapy, and geographic barriers. Therapist-guided internet-delivered CBT (iCBT) is a potential solution to this problem but is not generally available in our context.

The investigators plan to:

1. Develop a digital platform for the treatment of mental disorders using therapist-guided iCBT;

2. Assess the feasibility, acceptability, and potential effects of therapist-guided iCBT for adult obsessive-compulsive disorder (OCD) using the platform developed in Objective 1.

Conditions

Obsessive-Compulsive Disorder (OCD)

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Internet-delivered Cognitive Behavioral Therapy (iCBT)

Group Type: EXPERIMENTAL

icbt

Intervention Type: BEHAVIORAL

12-Week Therapist-Based iCBT for OCD (Adapted Version of OCD Net: https://therapistguide.webcbt.se/index.html)

Interventions

icbt

12-Week Therapist-Based iCBT for OCD (Adapted Version of OCD Net: https://therapistguide.webcbt.se/index.html)

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Age between 18 and 75
• Internet access
• Principal diagnosis of OCD, based on DSM-5
• Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) Total Severity Score > 16
• Ability to communicate in Spanish
• For participants taking psychotropic medication for OCD: at least eight weeks on stable medication and willingness to stay on the same medication/doses for the 12 weeks of the study

Exclusion Criteria

• Estimated IQ < 70, as per the Vocabulary subtest of the Wechsler Adults Intelligence Scale for Children (WISC)
• Eight or more previous sessions of CBT for OCD with an experienced therapist during the last 12 months
• Ongoing psychological treatment for OCD
• Diagnosis of organic brain disorder, intellectual disability, autism spectrum disorder, psychosis, bipolar disorder, low-weight anorexia nervosa, or alcohol/substance dependence
• Immediate risk to self or others (e.g., suicidality)
• Inability to communicate in Spanish
• Low motivation to participate (i.e., the patient does not believe the therapy will be helpful at all)
• Insufficient time to work on the treatment (about 30 minutes per day)

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Hospital Clinic of Barcelona

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Joaquim Radua, MD

Role: PRINCIPAL_INVESTIGATOR

Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS)

Central Contacts

Miquel A Fullana, PhD

Role: CONTACT

mafullana@clinic.cat

34+637908990

Maria Sagué, MD

Role: CONTACT

msague@clinic.cat

34 +932 27 54 00

Other Identifiers

HCB/2023/0643

Identifier Type: -

Identifier Source: org_study_id