Online Exposure Therapy for Obsessive-Compulsive Disorder (OCD) Study

NCT ID: NCT06470893

Last Updated: 2025-08-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 63 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-09-23
• Study Completion Date: 2025-07-23

Brief Summary

The overarching goal of this protocol is to investigate mechanisms that influence symptom outcomes of exposure and response prevention (ERP) therapy for OCD. Mechanisms may include affective processes, learning factors, cognitive factors, or other constructs that could influence treatment outcomes. The study team will conduct this research within the context of an effective online treatment for OCD called OCD-NET. OCD-NET is bibliotherapy with coaching and its content is reflective of standard care for OCD.

Conditions

Obsessive-Compulsive Disorder

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

OCD-NET Group

Participants will receive the OCD-NET intervention for up to 12 months.

Group Type: EXPERIMENTAL

OCD-NET

Intervention Type: BEHAVIORAL

OCD-NET is bibliotherapy with coaching and its content is reflective of standard care for OCD. OCD-NET is a self-paced intervention that participants complete entirely online with the support of an assigned individual therapist. Most participants complete this treatment in up to twelve weeks. On average, participants are expected to spend between one to five hours per week during the first half of treatment. In the second half of treatment when participants begin regular exposure and response prevention (ERP) exercises, participants are expected to spend about one hour per day.

Interventions

OCD-NET

OCD-NET is bibliotherapy with coaching and its content is reflective of standard care for OCD. OCD-NET is a self-paced intervention that participants complete entirely online with the support of an assigned individual therapist. Most participants complete this treatment in up to twelve weeks. On average, participants are expected to spend between one to five hours per week during the first half of treatment. In the second half of treatment when participants begin regular exposure and response prevention (ERP) exercises, participants are expected to spend about one hour per day.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• English-speaking
• Located within the United States
• 18-90 years old
• Able to provide consent
• Current diagnosis of OCD as assessed by clinical interview

Exclusion Criteria

• Adults unable to consent
• Individuals who are not yet adults (infants, children, teenagers)
• Participants currently located outside of the United States
• Prisoners
• Participants with hoarding as the primary OCD symptom
• Severe mental illness (e.g. schizophrenia, substance abuse); organic brain syndrome; or serious, current suicidal/homicidal ideation (based on phone screening or initial assessment)
• Concurrent enrollment in another psychotherapy treatment
• Participants taking psychotropic medication may be excluded if:

• They have started a brand new psychotropic medication within the last 12 weeks
• They have changed the dose of their psychotropic medication within the last 4 weeks
• They anticipate that they cannot maintain the current dose of their psychotropic medication for the duration of the study
• Participants may be excluded if they have any cognitive or physical impairments that would interfere with their participation (e.g., significant head injury, cognitive disability, dementia).

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 90 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Miami

OTHER

Sponsor Role: lead

Responsible Party

Kiara Timpano

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Kiara Timpano, PhD

Role: STUDY_CHAIR

University of Miami

Amelia Dev, MS

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

University of Miami

Miami, Florida, United States

Countries

United States

Other Identifiers

20240483

Identifier Type: -

Identifier Source: org_study_id