Effect of High Intensity Interval Exercise Training in Patients With Allergic Rhinitis

NCT ID: NCT06543251

Last Updated: 2024-08-07

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 36 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-06-01
• Study Completion Date: 2023-10-15

Brief Summary

The objective of this study was to compare the effects of training between high-intensity interval training and moderate continuous exercise training on the pulmonary function, respiratory muscle strength, symptoms of patients with allergic rhinitis, cytokines, and oxidative stress in patients with allergic rhinitis.

Detailed Description

36 patients with allergic rhinitis were divided into 3 groups, 12 people per group: the control group (CON), the group with high-intensity interval training at a ratio of 1:2 (HIIT) and the group with moderate continuous training (MCT), 3 days per week, over a total period of 12 weeks. Before and after the experiment, lung function, respiratory muscle strength, allergic rhinitis symptoms, nasal blood flow rate, peak nasal inspiratory flow, nitric oxide levels, cytokines and quality of life were measured and used for statistical analysis.

Conditions

Allergic Rhinitis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

High-intensity interval training group (HIIT)

the group with high-intensity interval training at a ratio of 1:2 (HIIT) 3 days per week, over a total period of 12 weeks.

Group Type: EXPERIMENTAL

High-intensity interval training group (HIIT)

Intervention Type: OTHER

The participants performed HIIT programs for 12 weeks involving walking/running on a treadmill preceded by a 10-min warm-up at low intensity and exercise with high intensity for 1 min at 85%-90% of the maximum heart rate alternating with low intensity at 50%-55% of the maximum heart rate for 2 min, for 24 minutes, and 10-min cool down.

Moderate continuous training group (MCT)

the group with moderate continuous training, 3 days per week, over a total period of 12 weeks.

Group Type: EXPERIMENTAL

Moderate continuous training group (MCT)

Intervention Type: OTHER

Subject participating in 30-min sessions for 12 weeks and Each session consisted of a 10-min warm up, walking/running on a treadmill 30 minutes at 65-70% Maximum Heart rate and 10-min cool down.

Sedentary control group (CON)

Group Type: OTHER

Sedentary control group (CON)

Intervention Type: OTHER

The control group had normal daily life.

Interventions

High-intensity interval training group (HIIT)

The participants performed HIIT programs for 12 weeks involving walking/running on a treadmill preceded by a 10-min warm-up at low intensity and exercise with high intensity for 1 min at 85%-90% of the maximum heart rate alternating with low intensity at 50%-55% of the maximum heart rate for 2 min, for 24 minutes, and 10-min cool down.

Intervention Type: OTHER

Moderate continuous training group (MCT)

Subject participating in 30-min sessions for 12 weeks and Each session consisted of a 10-min warm up, walking/running on a treadmill 30 minutes at 65-70% Maximum Heart rate and 10-min cool down.

Intervention Type: OTHER

Sedentary control group (CON)

The control group had normal daily life.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• A patient with allergic rhinitis who underwent a skin prick test and received a positive result.
• Patients with persistent allergic rhinitis, male and female, with symptoms of nasal congestion, sneezing, nasal itching, and runny nose for more than 4 days per week, and an average score of 7 or more in the past week using the allergic rhinitis symptom assessment questionnaire.
• stopped taking all medicine before the study such as antihistamine for 3 days, oral steroid and nasal steroid for at least 2 weeks and leukotriene receptor antagonist for at least a week prior to the study
• had no exercise program, non-smoking and without any food supplementation for at least 6 months prior to the start of the study
• Must not have other respiratory diseases such as bronchitis, pertussis, pneumonia, pneumonitis, aspergilloma, tuberculosis, asthma, lung cancer, emphysema, etc.
• Have a body mass index (BMI) between 18.5 and 24.9 kg/m².
• Complete the Physical Activity Readiness Questionnaire (PAR-Q+) by answering "no" to all questions.

Exclusion Criteria

• There is an unforeseen circumstance, such as an illness, that prevents participation in the research.
• Less than 80% of the research was completed.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Chulalongkorn University

OTHER

Sponsor Role: lead

Responsible Party

Wannaporn Tongtako, Ph.D.

Principal investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Wannaporn Tongtako, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Chulalongkorn University

Locations

Faculty of Sports Science, Chulalongkorn University

Pathum Wan, Bangkok, Thailand

Countries

Thailand

Other Identifiers

EX PHYSIO SPSC 11

Identifier Type: -

Identifier Source: org_study_id