Postoperative Pain in the Surgical Treatment of Hemorrhoids: Conventional Hemorrhoidectomy With a Monopolar Electric Scaler VS Bipolar Energy With Caiman® (Aesculap®)

NCT ID: NCT06535269

Last Updated: 2024-08-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-02

Study Completion Date

2025-07-31

Brief Summary

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To demonstrate that postoperative pain secondary to Milligan and Morgan hemorrhoidectomy with Caiman® (AESCULAP®) and subsequent oral conventional analgesia is at least not greater than that generated after hemorrhoidectomy with monopolar diathermy and intravenous analgesia with care home at discharge.

Detailed Description

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In the treatment of coloproctological pathology, one of the most important problems is postoperative pain. Especially in the management of hemorrhoids treatment. There are different approaches but in all of them pain is the predominant symptom.

There are some less painful techniques but the gold standard continues to be hemmorrhoidectomy, which is associated with postoperative pain. Some actions have been taken to control pain to avoid the admission of patients, but there are still problems in this regard.

Our group aims to study the effect of energy change for performing hemorrhoidectomy on postoperative pain.

Conditions

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Hemorrhoid Pain Hemorrhoidectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Non-inferiority, prospective, randomized, single-center, parallel-group clinical trial.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Control

Conventional hemorrhoidectomy with monopolar diathermy + intravenous analgesia with elastomeric pump + discharge with home hospitalization.

Group Type ACTIVE_COMPARATOR

Monopolar Hemorroidecotmy

Intervention Type PROCEDURE

Hemorrhoidectomy with monopolar diathermy

Experimental

conventional haemorrhoidectomy with Caiman® bipolar energy (AESCULAP®) + oral conventional analgesia + conventional home discharge.

Group Type EXPERIMENTAL

Caiman Hemorroidectomy

Intervention Type PROCEDURE

Hemorrhoidectomy with Caiman® bipolar energy

Interventions

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Monopolar Hemorroidecotmy

Hemorrhoidectomy with monopolar diathermy

Intervention Type PROCEDURE

Caiman Hemorroidectomy

Hemorrhoidectomy with Caiman® bipolar energy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All patients with 2 or 3 bundles of grade III-IV hemorrhoids (Goligher classification) clinically symptomatic and subject to outpatient hemorrhoidectomy
* Voluntary participation.
* ASA I-II-III.

* ASA IV.
* Allergic to Paracetamol, derivatives of morphine.
* Allergic to NSAIDs.
* Synchronous colorectal neoplasia.
* Coagulation disorders.
* Thrombosed hemorrhoid.
* Inflammatory bowel disease.
* Liver cirrhosis and/or portal hypertension.
* Pregnant women.
* Difficulty following up by phone and/or in person.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Corporacion Parc Tauli

OTHER

Sponsor Role lead

Responsible Party

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Laura Mora-Lopez

PhD, MD, Colorrectal Surgeon, Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Laura Mora

Role: PRINCIPAL_INVESTIGATOR

Parc Tauli University Hospital

Locations

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Laura Mora López

Sabadell, Barcelona, Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Laura Mora

Role: CONTACT

34 937211010 ext. 21490

Facility Contacts

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Laura Mora, Dr.

Role: primary

References

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Perera N, Liolitsa D, Iype S, Croxford A, Yassin M, Lang P, Ukaegbu O, van Issum C. Phlebotonics for haemorrhoids. Cochrane Database Syst Rev. 2012 Aug 15;2012(8):CD004322. doi: 10.1002/14651858.CD004322.pub3.

Reference Type BACKGROUND
PMID: 22895941 (View on PubMed)

Alonso-Coello P, Guyatt G, Heels-Ansdell D, Johanson JF, Lopez-Yarto M, Mills E, Zhou Q. Laxatives for the treatment of hemorrhoids. Cochrane Database Syst Rev. 2005 Oct 19;2005(4):CD004649. doi: 10.1002/14651858.CD004649.pub2.

Reference Type BACKGROUND
PMID: 16235372 (View on PubMed)

Shanmugam V, Thaha MA, Rabindranath KS, Campbell KL, Steele RJ, Loudon MA. Rubber band ligation versus excisional haemorrhoidectomy for haemorrhoids. Cochrane Database Syst Rev. 2005 Jul 20;2005(3):CD005034. doi: 10.1002/14651858.CD005034.pub2.

Reference Type BACKGROUND
PMID: 16034963 (View on PubMed)

Medina-Gallardo A, Curbelo-Pena Y, De Castro X, Roura-Poch P, Roca-Closa J, De Caralt-Mestres E. Is the severe pain after Milligan-Morgan hemorrhoidectomy still currently remaining a major postoperative problem despite being one of the oldest surgical techniques described? A case series of 117 consecutive patients. Int J Surg Case Rep. 2017;30:73-75. doi: 10.1016/j.ijscr.2016.11.018. Epub 2016 Nov 15.

Reference Type BACKGROUND
PMID: 27960130 (View on PubMed)

Nienhuijs S, de Hingh I. Conventional versus LigaSure hemorrhoidectomy for patients with symptomatic Hemorrhoids. Cochrane Database Syst Rev. 2009 Jan 21;2009(1):CD006761. doi: 10.1002/14651858.CD006761.pub2.

Reference Type BACKGROUND
PMID: 19160300 (View on PubMed)

Gentile M, De Rosa M, Carbone G, Pilone V, Mosella F, Forestieri P. LigaSure Haemorrhoidectomy versus Conventional Diathermy for IV-Degree Haemorrhoids: Is It the Treatment of Choice? A Randomized, Clinical Trial. ISRN Gastroenterol. 2011;2011:467258. doi: 10.5402/2011/467258. Epub 2010 Nov 21.

Reference Type BACKGROUND
PMID: 21991510 (View on PubMed)

World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013 Nov 27;310(20):2191-4. doi: 10.1001/jama.2013.281053. No abstract available.

Reference Type BACKGROUND
PMID: 24141714 (View on PubMed)

Chan AW, Tetzlaff JM, Altman DG, Laupacis A, Gotzsche PC, Krle A-Jeric K, Hrobjartsson A, Mann H, Dickersin K, Berlin JA, Dore CJ, Parulekar WR, Summerskill WS, Groves T, Schulz KF, Sox HC, Rockhold FW, Rennie D, Moher D. SPIRIT 2013 Statement: defining standard protocol items for clinical trials. Rev Panam Salud Publica. 2015 Dec;38(6):506-14.

Reference Type BACKGROUND
PMID: 27440100 (View on PubMed)

Other Identifiers

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TAUHEMOR

Identifier Type: -

Identifier Source: org_study_id

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