Topical Application of GTN 0.4% in the Treatment of Anismus Following Stapled Haemorrhoidopexy
NCT ID: NCT01279551
Last Updated: 2011-01-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2/PHASE3
40 participants
INTERVENTIONAL
2004-01-31
2010-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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GTN
In this arm the investigators administer local application of 0.4% nitroglycerin ointment and ketorolac tromethamine 10 mg
0.4% nitroglycerin ointment
Local endoanal application 2 times a day
Control
In this arm the investigators administer local application of lidocaine cloridrato 2.5% and ketorolac tromethamine 10 mg.
lidocaine cloridrato 2.5% ointment
Local endoanal application of lidocaine cloridrato 2.5% ointment 2 times a day
Interventions
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0.4% nitroglycerin ointment
Local endoanal application 2 times a day
lidocaine cloridrato 2.5% ointment
Local endoanal application of lidocaine cloridrato 2.5% ointment 2 times a day
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Adults aged ≤ 75, male or female
Exclusion Criteria
18 Years
75 Years
ALL
No
Sponsors
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University of Roma La Sapienza
OTHER
Principal Investigators
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Francesco Saverio Mari, MD
Role: PRINCIPAL_INVESTIGATOR
Oneday-Day Surgery Unit, II Faculty of Medicne and Surgery, Sapienza University of Rome
Luigi Masoni, MD
Role: STUDY_CHAIR
Oneday-Day Surgery Unit, II Faculty of Medicne and Surgery, Sapienza University of Rome
Locations
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Oneday-Day Surgery Unit, II Faculty of Medicne and Surgery, Sapienza University of Rome
Rome, , Italy
Countries
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References
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Mari FS, Nigri G, Dall'Oglio A, Cosenza UM, Milillo A, Terrenato I, Pancaldi A, Brescia A. Topical glyceryl trinitrate ointment for pain related to anal hypertonia after stapled hemorrhoidopexy: a randomized controlled trial. Dis Colon Rectum. 2013 Jun;56(6):768-73. doi: 10.1097/DCR.0b013e31828b282c.
Other Identifiers
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DS-003
Identifier Type: -
Identifier Source: org_study_id
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