Assessment of Facial Symmetry After Facial Reconstruction Using Three-dimensional Stereophotogrammetry

NCT ID: NCT06534970

Last Updated: 2025-11-20

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-06-03
• Study Completion Date: 2027-06-30

Brief Summary

Facial reconstruction follows removal of a malignant or benign tumor of the oral cavity or face, complex facial trauma, or resection of osteonecrosis of the jaws. It's a challenge that aims to restore not only the functions of the face, but also its aesthetics, which is just as crucial. A poor aesthetic result after facial reconstruction has a serious impact on patient's lives. To develop more personalized surgery, and to anticipate and correct poor results in the future, it is essential to better understand the factors associated with poor aesthetic results in this type of surgery, as well as their impact on the patient's life.

This means correctly assessing the aesthetic outcome of this surgery. Today, however, aesthetic evaluation criteria remain inadequate. A number of criteria are involved in facial attractiveness, and facial symmetry is a key factor. It is generally accepted that severe facial asymmetries considerably diminish facial attractiveness. Currently, aesthetic evaluation criteria (particularly symmetry) are based primarily on the subjective perception of the surgeon or patient. However, there is a need to be able to measure facial symmetry objectively.

Methods for assessing symmetry rely on the placement of anatomical landmarks and the calculation of Euclidean distance, which involves locating homologous landmarks on each side of the face and comparing the length ratios of all possible lines connecting the landmarks on each side. However, these techniques are based on measurements often on two-dimensional (2D) photographs and do not take into account the three-dimensional nature of the face. Methods for three-dimensional analysis of facial symmetry have been developed based on three-dimensional CT reconstructions. However, this technique implies the use of an irradiating imaging technique, not systematically indicated at a distance from surgery.

This study aims to validate a method for analyzing facial symmetry using three-dimensional stereophotogrammetry, to identify risk factors for facial asymmetry in patients who have undergone facial reconstruction, and to assess the impact of facial asymmetry on patients' quality of life.

Conditions

Facial Reconstruction

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Facial reconstruction patients

Reconstruction of the lower or middle third of the face using a pedicled flap or microanastomosed free flap following excision of a benign or malignant tumor of the oral cavity or face, osteonecrosis of the jaws, or traumatic loss of facial substance

Questionnaires

Intervention Type: OTHER

• SF-36 quality of life scale for general health inquiry
• Rosenberg Self-Esteem Scale
• Self-perception scale

Three-dimensional stereophotogrammetry

Intervention Type: DEVICE

Three stereoscopic photographs

Interventions

Questionnaires

• SF-36 quality of life scale for general health inquiry
• Rosenberg Self-Esteem Scale
• Self-perception scale

Intervention Type: OTHER

Three-dimensional stereophotogrammetry

Three stereoscopic photographs

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Male or female, 18 years of age or older,
• Patient having given non-opposition for participation in this study,
• Reconstruction of the lower or middle third of the face by pedicled flap or microanastomosed free flap following excision of a benign or malignant tumor of the oral cavity or face, osteonecrosis of the jaws, loss of facial traumatic substance,
• Surgery and routine follow-up performed in the 3 departments (maxillofacial surgery, ENT, plastic and reconstructive surgery) of the PROMOD cluster at Marseille's CHU Conception

Exclusion Criteria

• History of reconstruction of the lower or middle third of the face other than that being evaluated at one year for this study,
• Subjects covered by articles L1121-5 to 1121-8 of the French Public Health Code (minors, adults under guardianship, patients deprived of their liberty, pregnant or breast-feeding women),
• Persons who cannot read and understand the French language well enough to be able to give their non-opposition to participating in the research.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Fondation des Gueules Cassées

UNKNOWN

Sponsor Role: collaborator

Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

CREMIEUX François

Role: STUDY_DIRECTOR

AP-HM

Locations

Assistance Publique - Hôpitaux de Marseille

Marseille, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Nicolas GRAILLON, MD

Role: CONTACT

nicolas.graillon@ap-hm.fr

04 91 43 6319 ext. +33

Facility Contacts

Nicolas GRAILLON, MD

Role: primary

nicolas.graillon@ap-hm.fr

04 91 43 63 19 ext. +33

Other Identifiers

RCAPHM23_0384

Identifier Type: -

Identifier Source: org_study_id

ID RCB

Identifier Type: OTHER

Identifier Source: secondary_id