Novel Imaging Techniques for the Characterization of Musculoskeletal Tumors II

NCT ID: NCT04394052

Last Updated: 2020-07-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

740 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-01

Study Completion Date

2030-06-01

Brief Summary

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This study aims at evaluating the value of various artificial intelligence based techniques to improve the characterization and image post-processing for patients with musculoskeletal tumors.

Detailed Description

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Comparison of values relating to the texture parameters of tumors evaluated by MRI and ultra-high resolution CT between benign and malignant lesions using histological analysis as the standard of reference.

Comparison of the diagnostic performance of texture parameters derived from different MRI sequences and ultra-high resolution CT for musculoskeletal tumor characterization.

Evaluate the impact of ultra-high resolution with respect to standard resolution on CT images Comparison of the diagnostic performance of the texture parameters for the tumor on the diagnostic performance of texture analysis derived parameters for the characterization of musculoskeletal tumors.

Evaluate the effectiveness and accuracy of automatic artificial intelligence (AI) based tumor segmentation tools.

Evaluate the use of trabecular analysis on ultra-high resolution CT images for the evaluation of tumor-bone interfaces.

Conditions

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Soft Tissue Neoplasm Bone Neoplasm

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Soft-tissue tumors

Benign and malignant soft tissue masses

MR imaging

Intervention Type DIAGNOSTIC_TEST

Medical imaging

Bone tumors

Benign and malignant bone focal bone lesions

MR imaging

Intervention Type DIAGNOSTIC_TEST

Medical imaging

Interventions

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MR imaging

Medical imaging

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Ultra-high resolution CT

Eligibility Criteria

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Inclusion Criteria

* Patients suspected to have a bone or soft-tissue tumor referred for imaging for initial tumors characterization and staging.

Exclusion Criteria

* Pregnancy
* Breast feeding patients
* Renal insufficiency
* Contra indications to MRI or CT
* Prior surgery or treatment to the evaluated lesion.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Lorraine Cancer Institute - ICL

UNKNOWN

Sponsor Role collaborator

Emille Gallé Surgical Center - CCEG

UNKNOWN

Sponsor Role collaborator

Diagnostic and Interventional Adaptative Imaging Laboratory - IADI

UNKNOWN

Sponsor Role collaborator

Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU-Nancy

Nancy, Lorraine, France

Site Status RECRUITING

Countries

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France

Central Contacts

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Pedro Gondim Teixieira, PhD

Role: CONTACT

+33 3 83 85 21 61

Gabriela Hossu, PhD

Role: CONTACT

+33 3 83 15 50 96

Facility Contacts

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Pedro Gondim Teixeira, Prof

Role: primary

+33383852161

Alain Blum, Prof

Role: backup

+33383852161

Other Identifiers

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2019PI253

Identifier Type: -

Identifier Source: org_study_id

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