Comparative Study Between Platelet Rich Plasma and Steroid Injection in Trigger Finger Treatment

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

PHASE3

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-07-24

Study Completion Date

2025-06-23

Brief Summary

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The goal of this clinical trial is to learn if platelet rich plasma works to treat early stage trigger finger in adults. It will also learn about the safety platelet rich plasma. The main questions it aims to answer are:

Does platelet rich plasma lower the pain associated with trigger finger of participants? Does it improve the hand grip strength and Q DASH score of participants? Researchers will compare platelet rich plasma to Depo-Medrol steroid (a known standard of care for early stage trigger finger) to see if platelet rich plasma works to treat early trigger finger.

Participants will:

Take platelet rich plasma or a depo-medrol steroid intralesional injection at recruitment into the intervention Visit the clinic once every 4 weeks for checkups and parameter measurements. Investigator will will keep a record of participants progress in symptom remission

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Detailed Description

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Conditions

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Trigger Finger Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

All participants will have the same assessment and have blood drawn for CBC. Opaque tape masking of the syringes will be done so that care giver and patients are not aware of interventional drug given.

Study Groups

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Group A

Patients here will have one milliliter of freshly prepared autologus platelet rich plasma injection for the treatment of their trigger finger.

Group Type EXPERIMENTAL

Platelet rich plasma

Intervention Type BIOLOGICAL

Freshly prepared autologus platelet rich plasma

Group B

Patients here will have one milliliter(20mg) injection of pfizer Depo-medrol(methylprednisolone acetate) injection for the treatment of their trigger finger.

Group Type ACTIVE_COMPARATOR

Pfizer Depo-medrol

Intervention Type DRUG

Methylprednisolone acetate 20mg/ml injection

Interventions

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Platelet rich plasma

Freshly prepared autologus platelet rich plasma

Intervention Type BIOLOGICAL

Pfizer Depo-medrol

Methylprednisolone acetate 20mg/ml injection

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients who are 18year and above with mild or moderate trigger finger, who are willing to have intra-lesional administration of blood product.

No previous treatment for the affected finger.

Exclusion Criteria

* Previous steroid injection
* Previous Surgery to that finger
* Thrombocytopenic patients
* Hand and finger contracture
* Rheumatoid arthritis of the finger

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No