The Impact of Jiaji Electroacupuncture and Scalp Electroacupuncture on Traumatic Spinal Cord Injury

NCT ID: NCT06509841

Last Updated: 2025-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-01

Study Completion Date

2025-03-30

Brief Summary

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Spinal cord injury (SCI), leads to functional deficits and complications like neurogenic bladder and deep vein thrombosis, imposing a global annual financial burden. This trial aims to compares Jiaji electroacupuncture (JEA) and scalp electroacupuncture (SEA) in SCI rehabilitation. This randomized controlled trial (RCT) compared JEA and SEA in SCI rehabilitation.

Detailed Description

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The motor function score, light touch score, and pinprick sensation score of both groups showed significant improvement ( P \< 0.001). When comparing Group A and Group B, there was no statistically significant difference in ASIA grade improvement at week 4 ( P \> 0.05), but at week 8 and the 3-month follow-up, the proportion of ASIA grade improvement in Group A was significantly higher than that in Group B (week 8: 40.48% vs. 14.29%, P=0.007; 3-month follow-up: 47.62% vs. 21.43%, P = 0.012). At week 4, week 8, and the 3-month follow-up, Group A's motor function score, light touch score, pinprick sensation score, and MBI were all higher than those of Group B ( P \< 0.05).

Conditions

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Spinal Cord Injuries (SCI)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Scalp electro-acupuncture

Recruiting patients receiving electro-acupuncture at the Scalp points

Group Type EXPERIMENTAL

Electro-acupuncture at the scalp points

Intervention Type OTHER

Adopting treatments for the group that received electro-acupuncture at the Scalp points, including: ① electro-acupuncture at the Scalp points with continuous treatment for 8 weeks.

Jiaji electro-acupuncture

Recruited patients receiving electro-acupuncture at the Jiaji points

Group Type EXPERIMENTAL

Electro-acupuncture at the Jiaji points

Intervention Type OTHER

Adopting treatments for the group that received electro-acupuncture at the Jiaji points, including: ① electro-acupuncture at the Jiaji points with continuous treatment for 8 weeks.

Interventions

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Electro-acupuncture at the Jiaji points

Adopting treatments for the group that received electro-acupuncture at the Jiaji points, including: ① electro-acupuncture at the Jiaji points with continuous treatment for 8 weeks.

Intervention Type OTHER

Electro-acupuncture at the scalp points

Adopting treatments for the group that received electro-acupuncture at the Scalp points, including: ① electro-acupuncture at the Scalp points with continuous treatment for 8 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. The duration of spinal cord injury must be between 3 to 6 months;
2. The site of injury must be clearly defined;
3. The cause of injury must be traumatic;
4. Patients must be over 18 years of age;
5. Patients must provide consent to participate in this study.

Exclusion Criteria

1. Unknown time or site of injury;
2. Disagreement to participate in this study;
3. Patients with contraindications for acupuncture intervention (such as skin lesions or rashes at potential acupuncture sites);
4. Patients with cognitive or language impairments who are unable to cooperate with scale evaluations.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hangzhou Medical College

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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the Affiliated Zhejiang Provincial People's Hospital to Hangzhou Medical College.

Hangzhou, Zhejiang, China

Site Status

Countries

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China

References

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Lucci VM, McGrath MS, Inskip JA, Sarveswaran S, Willms R, Claydon VE. Clinical recommendations for use of lidocaine lubricant during bowel care after spinal cord injury prolong care routines and worsen autonomic dysreflexia: results from a randomised clinical trial. Spinal Cord. 2020 Apr;58(4):430-440. doi: 10.1038/s41393-019-0381-2. Epub 2019 Nov 25.

Reference Type BACKGROUND
PMID: 31767947 (View on PubMed)

Dyson-Hudson TA, Kadar P, LaFountaine M, Emmons R, Kirshblum SC, Tulsky D, Komaroff E. Acupuncture for chronic shoulder pain in persons with spinal cord injury: a small-scale clinical trial. Arch Phys Med Rehabil. 2007 Oct;88(10):1276-83. doi: 10.1016/j.apmr.2007.06.014.

Reference Type BACKGROUND
PMID: 17908569 (View on PubMed)

Xiong F, Fu C, Zhang Q, Peng L, Liang Z, Chen L, He C, Wei Q. The Effect of Different Acupuncture Therapies on Neurological Recovery in Spinal Cord Injury: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Evid Based Complement Alternat Med. 2019 Oct 27;2019:2371084. doi: 10.1155/2019/2371084. eCollection 2019.

Reference Type BACKGROUND
PMID: 31772592 (View on PubMed)

Tang H, Guo Y, Zhao Y, Wang S, Wang J, Li W, Qin S, Gong Y, Fan W, Chen Z, Guo Y, Xu Z, Fang Y. Effects and Mechanisms of Acupuncture Combined with Mesenchymal Stem Cell Transplantation on Neural Recovery after Spinal Cord Injury: Progress and Prospects. Neural Plast. 2020 Sep 25;2020:8890655. doi: 10.1155/2020/8890655. eCollection 2020.

Reference Type BACKGROUND
PMID: 33061954 (View on PubMed)

Xiong F, Lu J, Pan H, Wang F, Huang Y, Liu Y, Li L, Zhang R, Wang Y, He C, Quan W. Effect of Specific Acupuncture Therapy Combined with Rehabilitation Training on Incomplete Spinal Cord Injury: A Randomized Clinical Trial. Evid Based Complement Alternat Med. 2021 Dec 26;2021:5671998. doi: 10.1155/2021/5671998. eCollection 2021.

Reference Type BACKGROUND
PMID: 34987595 (View on PubMed)

Jiang K, Sun Y, Chen X. Mechanism Underlying Acupuncture Therapy in Spinal Cord Injury: A Narrative Overview of Preclinical Studies. Front Pharmacol. 2022 Apr 7;13:875103. doi: 10.3389/fphar.2022.875103. eCollection 2022.

Reference Type BACKGROUND
PMID: 35462893 (View on PubMed)

Huang Y, He K, Fang D, Ni F, Qiu B, Liang K, Ma R. A bibliometric of research trends in acupuncture for spinal cord injury: Quantitative and qualitative analyses. Front Neurol. 2022 Sep 15;13:936744. doi: 10.3389/fneur.2022.936744. eCollection 2022.

Reference Type BACKGROUND
PMID: 36188361 (View on PubMed)

Fan Q, Cavus O, Xiong L, Xia Y. Spinal Cord Injury: How Could Acupuncture Help? J Acupunct Meridian Stud. 2018 Aug;11(4):124-132. doi: 10.1016/j.jams.2018.05.002. Epub 2018 May 30.

Reference Type BACKGROUND
PMID: 29753705 (View on PubMed)

Inzani F, Rindi G. Introduction to neuroendocrine neoplasms of the digestive system: definition and classification. Pathologica. 2021 Feb;113(1):1-4. doi: 10.32074/1591-951X-227.

Reference Type BACKGROUND
PMID: 33686304 (View on PubMed)

Other Identifiers

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202401

Identifier Type: -

Identifier Source: org_study_id

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