The Effect of Refractive Errors on Central Corneal Thickness by Using Pentacam and IOL Master

NCT ID: NCT06484894

Last Updated: 2024-07-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-07-15

Study Completion Date

2025-08-31

Brief Summary

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To evaluate the impact of refractive errors on the central corneal thickness obtained by Pentacam and intraocular lenses (IOL) master in eyes with different refractive errors.

Detailed Description

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Central corneal thickness (CCT) is a key indicator of corneal health status and helps to assess corneal diseases. The normal corneal thickness is about 540 μm and mainly consists of the stroma, which is estimated at 450 μm in the center. The stroma provides vital structural integrity and plays a key role in helping maintain transparency. It has been reported, however, that CCT follows a diurnal pattern being 10 μm thicker in the morning due to reduced evaporation of water from underneath the closed eyelids

Conditions

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Central Corneal Thickness

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Hypermetrope

Effect of hypermetropia on central corneal thickness by using pentacam and IOL master

Pentacam and IOL master

Intervention Type DEVICE

Device used for measurement of central corneal thickness

Emmetrope

Effect of emmetropia on central corneal thickness by using pentacam and IOL master

Pentacam and IOL master

Intervention Type DEVICE

Device used for measurement of central corneal thickness

Myopia

Effect of myopia on central corneal thickness by using pentacam and IOL master

Pentacam and IOL master

Intervention Type DEVICE

Device used for measurement of central corneal thickness

Interventions

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Pentacam and IOL master

Device used for measurement of central corneal thickness

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subjects included in this study aged between20 and 41 years, asked for refractive surgery

Exclusion Criteria

* patients with corneal scarrig or opacification.

* Patients with corneal dystrophies.
* Patients with keratoconus.
* Previous ocular or refractive surgery.
* Ocular trauma.
* Uveitis patients.
* Patients with history of recent contact lens wear.
Minimum Eligible Age

20 Years

Maximum Eligible Age

41 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Haidy Nayer Adly

Resident doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mahmoud Fathy rateb, Professor

Role: STUDY_DIRECTOR

Assiut University

Ahmed Abd el Nasser awad, Lecturer

Role: STUDY_CHAIR

Assiut University

Mohamed Tarek Abd el menaam, Professor

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Central Contacts

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Haidy Nayer Adly, Master

Role: CONTACT

01277603313

References

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Wang Q, Liu W, Wu Y, Ma Y, Zhao G. Central corneal thickness and its relationship to ocular parameters in young adult myopic eyes. Clin Exp Optom. 2017 May;100(3):250-254. doi: 10.1111/cxo.12485. Epub 2016 Oct 18.

Reference Type BACKGROUND
PMID: 27757993 (View on PubMed)

Prasad A, Fry K, Hersh PS. Relationship of age and refraction to central corneal thickness. Cornea. 2011 May;30(5):553-5. doi: 10.1097/ICO.0b013e3181fb880c.

Reference Type BACKGROUND
PMID: 21107245 (View on PubMed)

Other Identifiers

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Central corneal thickness

Identifier Type: -

Identifier Source: org_study_id

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