Dysfunction of Olfaction After COVID-19 Infection: Morphological and Histomolecular Investigation
NCT ID: NCT06482138
Last Updated: 2025-03-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
240 participants
INTERVENTIONAL
2024-01-24
2026-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Control
Biopsy and cytobrush during a scheduled structural intervention in general anesthesia
Biopsy and Cytobrush
Collection of olfactory cleft biopsies and cytobrushes
Olfactory Dysfunction
Biopsy and cytobrush during consultation in local anesthesia
Biopsy and Cytobrush
Collection of olfactory cleft biopsies and cytobrushes
Interventions
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Biopsy and Cytobrush
Collection of olfactory cleft biopsies and cytobrushes
Eligibility Criteria
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Inclusion Criteria
* Control group: No OD (TDI-score \>30.5.)
Exclusion Criteria
* Use of anticoagulation therapy
* Allergy to local anesthetics
18 Years
70 Years
ALL
No
Sponsors
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University Hospital, Geneva
OTHER
Max Planck Research Unit for Neurogenetics
UNKNOWN
University Hospital Carl Gustav Carus
OTHER
University of Zurich
OTHER
Universitaire Ziekenhuizen KU Leuven
OTHER
Responsible Party
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Principal Investigators
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Laura van Gerven
Role: PRINCIPAL_INVESTIGATOR
UZ/KU Leuven
Locations
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Cliniques Universitaires Saint-Luc
Brussels, Brussels Capital, Belgium
UZ/KU Leuven
Leuven, Vlaams-Brabant, Belgium
AZ Sint-Jan Brugge
Bruges, West-Vlaanderen, Belgium
University Hospital Carl Gustav Carus
Dresden, Dresden, Germany
Max Planck Research Unit for Neurogenetics
Frankfurt am Main, Frankfurt, Germany
Hôpitaux Universitaires de Genève
Geneva, Canton of Geneva, Switzerland
University of Zurich and University Hospital Zurich
Zurich, Canton of Zurich, Switzerland
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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S67380
Identifier Type: -
Identifier Source: org_study_id
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