Efficacy of Olfactive Training on Loss of Smell and Taste Caused by SARS CoV2 COVID-19 (Covid-Smell)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-11-18

Study Completion Date

2022-03-09

Brief Summary

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The purpose of this study is to evaluate efficiency of two months of olfactive training on olfactory and taste loss secondary to covid-19. We will compare 2 groups : olfactive training group versus no olfactive training group.

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Olfactory Dysfunction

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Detailed Description

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The purpose of this study is to evaluate efficiency of two months of olfactive training on olfactory and taste loss secondary to covid-19. We will compare 2 groups : olfactive training group versus no olfactive training group.

Conditions

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COVID - 19

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

To prove this efficiency, a parallel prospective comparative study appear to be one of the best the way.

Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Caregivers

Study Groups

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olfactory training arm

with a daily olfactory training during 2 month

Group Type EXPERIMENTAL

Olfactory rehabilitation consists of smelling a series of spices every day for 2 months

Intervention Type OTHER

Olfactory rehabilitation consists of smelling a series of spices every day for 2 months: vanilla, coffee, dill, thyme, cinnamon, cloves, lavender, coriander, light vinegar, mint, and cumin.

This rehabilitation is based on the protocols proposed by SFORL (French ORL society) and Oleszkiewicz et al.8

Allergies to certain spices will be noted at the start of the study:

* in known allergy: change by another spice which belongs to the same chemical category.
* in case of allergies to several scents: patient is not included in the study.
* in case of allergy appearing during participation: clinical evaluation by ENT, change by another spice which belongs to the same chemical category.
* in case of allergies to several scents occuring during participation: patient is excluded from the study.

no olfactory training

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Olfactory rehabilitation consists of smelling a series of spices every day for 2 months

Olfactory rehabilitation consists of smelling a series of spices every day for 2 months: vanilla, coffee, dill, thyme, cinnamon, cloves, lavender, coriander, light vinegar, mint, and cumin.

This rehabilitation is based on the protocols proposed by SFORL (French ORL society) and Oleszkiewicz et al.8

Allergies to certain spices will be noted at the start of the study:

* in known allergy: change by another spice which belongs to the same chemical category.
* in case of allergies to several scents: patient is not included in the study.
* in case of allergy appearing during participation: clinical evaluation by ENT, change by another spice which belongs to the same chemical category.
* in case of allergies to several scents occuring during participation: patient is excluded from the study.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* SARS-CoV-2 infection suspect or confirmed
* supported by CHU Guadeloupe
* with brutal olfactory or taste loss
* affiliated or beneficiary of a social security scheme
* informed consent signed

Exclusion Criteria

* recent rhinosinusitis, less than 6 months
* lingual pathology
* communication disorder
* Patients subject to a justice safeguard
* Allergy to several spices that are part of the rehabilitation set
* Pregnant or breastfeeding women
* Absence of signed consent

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No