E-mails to Nudge Safer and Better-Informed Prescribing of Risky Drugs

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

7872 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-07-17

Study Completion Date

2025-12-31

Brief Summary

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This study will test e-mails to encourage engagement with the Minnesota prescription monitoring program (PMP/PDMP) and will evaluate the effect of these e-mails on PMP/PDMP use and controlled substance prescribing.

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Detailed Description

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Drug overdose deaths have skyrocketed in recent years, and many overdoses continue to involve prescribed medications like opioids and stimulants. At the same time, state prescription drug monitoring programs (PDMPs), which help clinicians prescribe these medications safely, remain underused. In Minnesota, 32% of opioid prescriptions are written by clinicians who do not use the PDMP. In many states, including Minnesota, policymakers have limited tools to raise PDMP use even though it is often required under state law. To address this policy dilemma, this study will test e-mails designed to facilitate PDMP use and evaluate their effects on PDMP use and controlled substance prescribing. This study will include a projected 7,126 physician and physician assistant prescribers of opioids and other controlled substances who lack active PDMP accounts, never query the PDMP, or query the PDMP infrequently relative to their prescribing volume. To generate evidence on clinician motivation for responding to encouragement, the study will randomly vary messaging to focus on legal requirements to use the PDMP vs. clinical benefits of the PDMP.

Conditions

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Opioid Prescribing Prescription Drug Misuse

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Clinicians will be assigned at random to one of three arms: PDMP legal mandate e-mails, PDMP clinical benefit emails, or a control group.

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Legal Mandate Messaging

Group Type EXPERIMENTAL

PDMP Legal Mandate E-mail

Intervention Type BEHAVIORAL

E-mails highlighting the state's legal requirements to use the PDMP. There will be one initial email and one follow-up email one month later.

Clinical Benefit Messaging

Group Type EXPERIMENTAL

PDMP Clinical Benefit E-mail

Intervention Type BEHAVIORAL

E-mails highlighting the clinical benefits of having access to the PDMP and checking the PDMP before prescribing opioids. There will be one initial email and one follow-up email one month later.

Control

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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PDMP Legal Mandate E-mail

E-mails highlighting the state's legal requirements to use the PDMP. There will be one initial email and one follow-up email one month later.

Intervention Type BEHAVIORAL

PDMP Clinical Benefit E-mail

E-mails highlighting the clinical benefits of having access to the PDMP and checking the PDMP before prescribing opioids. There will be one initial email and one follow-up email one month later.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Minnesota physician or physician assistant
* Controlled substance prescriber not following state requirements to maintain an active PDMP account, or opioid prescriber not searching the PDMP or infrequently searching the PDMP